Complex roads from genotype to phenotype in dilated cardiomyopathy: scientific update from the Working Group of Myocardial Function of the European Society of …

A Bondue, E Arbustini, A Bianco… - Cardiovascular …, 2018 - academic.oup.com
Dilated cardiomyopathy (DCM) frequently affects relatively young, economically, and
socially active adults, and is an important cause of heart failure and transplantation. DCM is …

Dilated cardiomyopathy in the era of precision medicine: latest concepts and developments

N Orphanou, E Papatheodorou, A Anastasakis - Heart failure reviews, 2022 - Springer
Dilated cardiomyopathy (DCM) is an umbrella term entailing a wide variety of genetic and
non-genetic etiologies, leading to left ventricular systolic dysfunction and dilatation, not …

Genetics of dilated cardiomyopathy: clinical implications

A Paldino, G De Angelis, M Merlo, M Gigli… - Current cardiology …, 2018 - Springer
Abstract Purpose of Review This review aims to summarize the current knowledge on the
genetic background of dilated cardiomyopathy (DCM), with particular attention to the …

Dilated cardiomyopathy: a new insight into the rare but common cause of heart failure

P Giri, A Mukhopadhyay, M Gupta, B Mohapatra - Heart Failure Reviews, 2022 - Springer
Heart failure is a global health burden responsible for high morbidity and mortality with a
prevalence of greater than 60 million individuals worldwide. One of the major causes of …

Genetic causes of dilated cardiomyopathy

V Favalli, A Serio, M Grasso, E Arbustini - Heart, 2016 - heart.bmj.com
Cardiomyopathies (CMPs) are “myocardial diseases characterized by structurally and
functionally abnormal heart muscle and absence of other diseases sufficient to cause the …

Familial dilated cardiomyopathy

S Peters, R Johnson, S Birch, D Zentner… - Heart, Lung and …, 2020 - Elsevier
Advances in human genome sequencing have re-invigorated genetics studies of dilated
cardiomyopathy (DCM), facilitating genetic testing and clinical applications. With a range of …

Genetics of Dilated Cardiomyopathy

R Eldemire, L Mestroni… - Annual review of medicine, 2024 - annualreviews.org
Dilated cardiomyopathy (DCM) is defined as dilation and/or reduced function of one or both
ventricles and remains a common disease worldwide. An estimated 40% of cases of familial …

Genetics of dilated cardiomyopathy

Y Fu, HJ Eisen - Current cardiology reports, 2018 - Springer
Abstract Purpose of Review Dilated cardiomyopathy (DCM) is characterized by left
ventricular dilation and systolic function and is the most common among all …

[HTML][HTML] Targeted next-generation sequencing of candidate genes reveals novel mutations in patients with dilated cardiomyopathy

Y Zhao, Y Feng, YM Zhang… - International …, 2015 - spandidos-publications.com
Dilated cardiomyopathy (DCM) is a major cause of sudden cardiac death and heart failure,
and it is characterized by genetic and clinical heterogeneity, even for some patients with a …

The rationale and timing of molecular genetic testing for dilated cardiomyopathy

A Morales, RE Hershberger - Canadian Journal of Cardiology, 2015 - Elsevier
The genetic evaluation of dilated cardiomyopathy (DCM) has been challenging, owing in
large part to marked genetic heterogeneity. However, lower costs from next-generation …