Cardiovascular (CV) disease (CVD) accounts for> 50% of deaths with known causes in
patients on dialysis. Elevated serum phosphorus levels are an important nontraditional risk …

Consequences and management of hyperphosphatemia in patients with renal insufficiency.
Progressive renal insufficiency leads to hyperphosphatemia, hypocalcemia, and secondary …

Particularly because the risk of harm cannot be safely excluded, the use of phosphate
binders in chronic kidney disease (CKD) patients demands caution. Yet, the clinical inertia …

Intracellular phosphate is critical for cellular processes such as signaling, nucleic acid
synthesis, and membrane function. Extracellular phosphate (Pi) is an important component …

Most patients receiving dialysis rely on dietary restriction and phosphate binders to minimize
the risk of hyperphosphatemia, which is associated with increased mortality. However …

Phosphate is essential in living organisms and its blood levels are regulated by a complex
network involving the kidneys, intestine, parathyroid glands, and the skeleton. The crosstalk …

A Phosphate Centric Forum, supported by Genzyme Corporation, was held on 24–25 June,
2010 at the Sheraton West Park Hotel, Munich, Germany, in which 25 medical and scientific …

The kidneys excrete excess dietary phosphate, and patients with chronic kidney disease
may suffer from phosphate overload and hyperphosphatemia. In chronic kidney disease …

Hyperphosphatemia in dialysis patients is routinely attributed to nonadherence to diet,
prescribed phosphate binders, or both. The role of individual patient variability in other …

Phosphorus is an essential element for life but is a rare element in the universe. On Earth, it
occurs mostly in the form of phosphates that are widespread but predominantly at very low …