The epidemic of obesity contributes to the burden of type 2 diabetes mellitus (T2DM) in the
United States and worldwide. Importantly, obesity is not only preventable but can be treated …

Abstract Purpose of Review The focus of this review is to discuss obesity, physical activity
(and physical inactivity/sedentary behavior), cardiovascular disease (CVD), and their often …

Overweight and obesity are well-established risk factors for most cardiovascular diseases
(CVD), including coronary heart disease (CHD), heart failure (HF), and atrial fibrillation …

Health authorities worldwide recommend weight loss as a primary endpoint for effective
obesity management. Despite a growing public awareness of the importance of weight loss …

In the present review, it is argued that while weight loss is associated with substantial
reduction in obesity-related cardiovascular disease risk and remains a desired outcome of …

Obesity is associated with increased prevalence of cardiovascular (CV) disease (CVD) risk
factors, which may adversely impact CV structure and function and may increase the …

We propose a weight-neutral strategy for obesity treatment on the following grounds:(1) the
mortality risk associated with obesity is largely attenuated or eliminated by moderate-to-high …

Obesity, particularly abdominal adiposity, is increasingly recognized as a cause of elevated
cardiometabolic risk—the risk of developing type 2 diabetes mellitus (DM) and …

Cardiorespiratory fitness (CRF) is a more powerful predictor of mortality than body mass
index or adiposity, and improving CRF is more important than losing body fat for reducing …

Although obesity is generally perceived as causing prejudice to heart health, there is
considerable individual metabolic heterogeneity among equally overweight or obese …