Neuronal networks, especially those in the central nervous system (CNS), evolved to
support extensive functional capabilities while ensuring stability. Several physiological …

Background: How effectively the brain can respond to injury and undergo structural repair
has become one of the most exciting areas of contemporary basic and translational …

Decades of basic science have clearly demonstrated the capacity of the central nervous
system (CNS) to structurally and functionally adapt in response to experience. The field of …

The past 20 years have represented an important period in the development of principles
underlying neuroplasticity, especially as they apply to recovery from neurological injury. It is …

Contrary to the classical view of a pre-determined wiring pattern, there is considerable
evidence that cortical representation of body parts is continuously modulated in response to …

Following brain injury or disease there are widespread biochemical, anatomical and
physiological changes that result in what might be considered a new, very different brain …

With the development of neuroscience, substantial advances have been achieved in
peripheral nerve regeneration over the past decades. However, peripheral nerve injury …

Injuries to the peripheral nerves result in partial or total loss of motor, sensory, and
autonomic functions in the denervated segments of the body due to the interruption of axons …

The Department of Rehabilitation Medicine, Nippon Medical School In recent years, our
understanding of motor learning, neuroplasticity and functional recovery after the occurrence …

A fundamental property of the brain is its capacity to change with a wide variety of
experiences, including injury. Although there are spontaneous reparative changes following …