Schizophrenia is modelled as a neurodevelopmental disease with high heritability.
However, established markers like cortical thickness and grey matter volume are heavily …

OBJECTIVE: Cerebral gyrification is attributed to a large extent to genetic and
intrauterine/perinatal factors. Hence, investigating gyrification might offer important evidence …

Schizophrenia is believed to be a neurodevelopmental disease with high heritability.
Differential diagnosis is often challenging, especially in early phases, namely with other …

Aim Increased brain gyrification in diverse cortical regions has been reported in patients with
schizophrenia, possibly reflecting deviations in early neurodevelopment. However, it …

Background: Cortical thickness (CT) and gyrification are complementary indices that assess
different aspects of gray matter structural integrity. Both neurodevelopment insults and acute …

Previous magnetic resonance imaging (MRI) studies reported increased brain gyrification in
schizophrenia and schizotypal disorder, a prototypic disorder within the schizophrenia …

Previous neuroimaging studies of gyrification, a possible marker of early neurodevelopment,
in schizophrenia patients have reported inconsistent results. In addition, it remains unclear …

BACKGROUND: A number of studies have found localized differences in the appearance
and extent of cortical folding between the brains of schizophrenic patients and healthy …

Several studies have sought to test the neurodevelopmental hypothesis of schizophrenia
through analysis of cortical gyrification. However, to date, results have been inconsistent. A …

To investigate the hypothesis that patients with schizophrenia exhibit gross cortical
abnormalities of developmental origin, we utilized the gyrification index (GI)(ratio of inner to …