Synthesis and biological evaluation of some novel thiazole-based heterocycles as potential anticancer and antimicrobial agents

S Abu-Melha, MM Edrees, HH Salem, NA Kheder… - Molecules, 2019 - mdpi.com
A novel series of thiazole-based heterocycles was synthesized using 1, 3-dipolar
cycloaddition reactions in the presence of chitosan-grafted-poly (vinylpyridine) as an eco …

Synthesis, characterization and in vitro anticancer activity of thiabendazole-derived 1, 2, 3-triazole derivatives

K El Bourakadi, MEM Mekhzoum, C Saby… - New Journal of …, 2020 - pubs.rsc.org
A series of thiabendazole-derived 1, 2, 3-triazole compounds were synthesized in good
yields via 1, 3-dipolar cycloaddition through click chemistry approach using different chain …

Eco-friendly synthesis, characterization and biological evaluation of some novel pyrazolines containing thiazole moiety as potential anticancer and antimicrobial …

MM Edrees, SA Melha, AM Saad, NA Kheder… - Molecules, 2018 - mdpi.com
The one-pot synthesis of a series of pyrazoline derivatives containing the bioactive thiazole
ring has been performed through a 1, 3-dipolar cycloaddition reaction of N …

One-pot synthesis of novel thiazoles as potential anti-cancer agents

AR Sayed, SM Gomha, EA Taher… - Drug design …, 2020 - Taylor & Francis
Background Thiazole and thiosemicarbazone derivatives are known to have potential
anticancer activity with a mechanism of action related to inhibition of matrix metallo …

Design, synthesis and anticancer evaluation of new substituted thiophene-quinoline derivatives

DIA Othman, KB Selim, AA Magda, AS Tantawy… - Bioorganic & Medicinal …, 2019 - Elsevier
A series of new isoxazolyl, triazolyl and phenyl based 3-thiophen-2-yl-quinoline derivatives
were synthesized adopting click chemistry approach. In addition, the synthesis of new useful …

Synthesis and Characterization of Some New Bis-Pyrazolyl-Thiazoles Incorporating the Thiophene Moiety as Potent Anti-Tumor Agents

SM Gomha, MM Edrees, FMA Altalbawy - International journal of …, 2016 - mdpi.com
A new series of 1, 4-bis (1-(5-(aryldiazenyl) thiazol-2-yl)-5-(thiophen-2-yl)-4, 5-dihydro-1 H-
pyrazol-3-yl) benzenes 3a–i were synthesized via reaction of 5, 5′-(1, 4-phenylene) bis (3 …

Pharmacological evaluation of some novel synthesized compounds derived from spiro (cyclohexane-1, 2′-thiazolidines)

EM Flefel, HH Sayed, AI Hashem, EA Shalaby… - Medicinal Chemistry …, 2014 - Springer
A series of novel spiro (cyclohexane-1, 2′-thiazolidine) derivatives 1–5 and spiro
(cyclohexane1, 2′-thiazolo-pyridine) derivatives 6–14 were synthesized. Arylidene …

Synthesis, Characterization, and Biological Evaluation of Some Novel Pyrazolo[5,1-b]thiazole Derivatives as Potential Antimicrobial and Anticancer Agents

A Alsayari, AB Muhsinah, YI Asiri, FA Al-Aizari… - Molecules, 2021 - mdpi.com
The pharmacological activities of thiazole and pyrazole moieties as antimicrobial and
anticancer agents have been thoroughly described in many literature reviews. In this study …

Design, click synthesis, anticancer screening and docking studies of novel benzothiazole-1, 2, 3-triazoles appended with some bioactive benzofused heterocycles

MR Aouad, MA Almehmadi, N Rezki, FF Al-blewi… - Journal of Molecular …, 2019 - Elsevier
Abstract New series of benzothiazole-1, 2, 3-triazoles; appended with benzothiazole, isatin
and/or benzimidazole moiety; were designed and synthesized through the click chemistry …

[PDF][PDF] Synthesis of some novel thiazole, thiadiazole and 1, 4-phenylene-bis-thiazole derivatives as potent antitumor agents

SM Gomha, FM Abdelrazek, AH Abdelrahman… - Heterocycles, 2016 - academia.edu
A novel series of 2-ethylidenehydrazono-5-arylazothiazoles 5a-h and 2-
ethylidenehydrazono-5-arylazothiazolones 9a-d were prepared by cyclocondensation of …