The role of matrix metalloproteinases (MMP‐2 and MMP‐9) in ageing and longevity: Focus on sicilian long‐living individuals (LLIs)
P Cancemi, A Aiello, G Accardi… - Mediators of …, 2020 - Wiley Online Library
Extracellular matrix metalloproteinases (MMPs) are a group of proteins that activate
substrates by enzymatic cleavage and, on the basis of their activities, have been …
substrates by enzymatic cleavage and, on the basis of their activities, have been …
Age-and gender-dependent changes in connective tissue remodeling: physiological differences in circulating MMP-3, MMP-10, TIMP-1 and TIMP-2 level
K Komosinska-Vassev, P Olczyk, K Winsz-Szczotka… - Gerontology, 2010 - karger.com
Background: The mechanisms which cause age-dependent remodeling of connective tissue
are still not fully understood. Matrix metalloproteinases (MMPs) and tissue inhibitors of …
are still not fully understood. Matrix metalloproteinases (MMPs) and tissue inhibitors of …
Role of Proinflammatory Alleles in Longevity and Atherosclerosis: Results of Studies Performed on− 1562C/T MMP‐9 in Centenarians and Myocardial Infarction …
Centenarians are characterized by marked delay or escape from age‐associated diseases
that cause mortality at earlier ages. Jointly, atherosclerosis and its complications, such as …
that cause mortality at earlier ages. Jointly, atherosclerosis and its complications, such as …
Mediterranean diet and plasma concentration of inflammatory markers in old and very old subjects in the ZINCAGE population study
GV Dedoussis, S Kanoni, E Mariani… - Clinical chemistry and …, 2008 - degruyter.com
Background: Aging is associated with low-grade elevation of circulating inflammatory
markers, leading to increased risk of morbidity and mortality. The Mediterranean diet has …
markers, leading to increased risk of morbidity and mortality. The Mediterranean diet has …
Effects of age, gender, ethnicity, diurnal variation and exercise on circulating levels of matrix metalloproteinases (MMP)-2 and-9, and their inhibitors, tissue inhibitors of …
MH Tayebjee, GYH Lip, AD Blann, RJ MacFadyen - Thrombosis research, 2005 - Elsevier
Background: Circulating metalloproteinases (MMP) and their inhibitors (TIMP) are indices of
vascular and cardiac tissue matrix turnover. However, the temporal changes and …
vascular and cardiac tissue matrix turnover. However, the temporal changes and …
[HTML][HTML] Biomarkers of extracellular matrix metabolism (MMP-9 and TIMP-1) and risk of stroke, myocardial infarction, and cause-specific mortality: cohort study
Objective Turnover of the extracellular matrix in all solid organs is governed mainly by a
balance between the degrading matrix metalloproteinases (MMPs) and their tissue inhibitors …
balance between the degrading matrix metalloproteinases (MMPs) and their tissue inhibitors …
[HTML][HTML] Prospective study of matrix metalloproteinase-9 and risk of myocardial infarction and stroke in older men and women
BJ Jefferis, P Whincup, P Welsh, G Wannamethee… - Atherosclerosis, 2010 - Elsevier
OBJECTIVES: The endopeptidase matrix metalloproteinase-9 (MMP-9) is implicated in
atherosclerotic plaque rupture. We investigate prospective associations between MMP-9 …
atherosclerotic plaque rupture. We investigate prospective associations between MMP-9 …
[HTML][HTML] Circulating matrix metalloproteinase-9 is associated with cardiovascular risk factors in a middle-aged normal population
P Garvin, L Nilsson, J Carstensen, L Jonasson… - PloS one, 2008 - journals.plos.org
Background Elevated levels of circulating matrix metalloproteinase-9 (MMP-9) have been
demonstrated in patients with established coronary artery disease (CAD). The aim of this …
demonstrated in patients with established coronary artery disease (CAD). The aim of this …
Serum matrix metalloproteinase‐9 is elevated in men with a history of myocardial infarction
J Renko, A Kalela, O Jaakkola, S Laine… - … journal of clinical and …, 2004 - Taylor & Francis
Elevated serum inflammatory markers have been reported in coronary heart disease. Levels
of serum matrix metalloproteinase‐9 (MMP‐9), C‐reactive protein (CRP), C3‐complement …
of serum matrix metalloproteinase‐9 (MMP‐9), C‐reactive protein (CRP), C3‐complement …
Elevated MMP‐8 and Decreased Myeloperoxidase Concentrations Associate Significantly with the Risk for Peripheral Atherosclerosis Disease and Abdominal Aortic …
P Pradhan‐Palikhe, P Vikatmaa… - Scandinavian …, 2010 - Wiley Online Library
Matrix metalloproteinases are responsible for degradation and remodelling of extracellular
matrix and exert important roles in initiation and progression of inflammatory diseases. We …
matrix and exert important roles in initiation and progression of inflammatory diseases. We …