[HTML][HTML] Cell-penetrating peptides in protein mimicry and cancer therapeutics

M Zorko, S Jones, Ü Langel - Advanced drug delivery reviews, 2022 - Elsevier
Extensive research has been undertaken in the pursuit of anticancer therapeutics. Many
anticancer drugs require specificity of delivery to cancer cells, whilst sparing healthy tissue …

Cell-penetrating peptides: strategies for anticancer treatment

D Raucher, JS Ryu - Trends in molecular medicine, 2015 - cell.com
Cell-penetrating peptides (CPP) provide an efficient strategy for the intracellular delivery of
bioactive molecules in various biomedical applications. This review focuses on recent …

Delivery of various cargos into cancer cells and tissues via cell-penetrating peptides: A review of the last decade

A Shoari, R Tooyserkani, M Tahmasebi, DWPM Löwik - Pharmaceutics, 2021 - mdpi.com
Abstracts Cell-penetrating peptides (CPPs), also known as protein transduction domains,
are a class of diverse amino acid sequences with the ability to cross cellular membranes …

Recent advances in cell penetrating peptide-based anticancer therapies

J Habault, JL Poyet - Molecules, 2019 - mdpi.com
Cell-penetrating-peptides (CPPs) are small amino-acid sequences characterized by their
ability to cross cellular membranes. They can transport various bioactive cargos inside cells …

Cell-penetrating and cell-targeting peptides in drug delivery

E Vivès, J Schmidt, A Pèlegrin - … et Biophysica Acta (BBA)-Reviews on …, 2008 - Elsevier
During the last decade, the potential of peptides for drug delivery into cells has been
highlighted by the discovery of several cell-penetrating peptides (CPPs). CPPs are very …

Recent in vivo advances in cell-penetrating peptide-assisted drug delivery

K Kurrikoff, M Gestin, Ü Langel - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Delivery of macromolecular drugs is an important field in medical research.
However, macromolecules are usually unable to cross the cell membrane without the …

Bioactive cell penetrating peptides and proteins in cancer: a bright future ahead

T Jauset, ME Beaulieu - Current Opinion in Pharmacology, 2019 - Elsevier
Highlights•Many key engines of cancer remain undruggable by conventional approaches.•
Therapeutic peptides and proteins promise to drug challenging cancer …

Cancer targeting peptides

M Kalmouni, S Al-Hosani, M Magzoub - Cellular and Molecular Life …, 2019 - Springer
Despite continuing advances in the development of biomacromolecules for therapeutic
purposes, successful application of these often large and hydrophilic molecules has been …

Recent innovations in peptide based targeted drug delivery to cancer cells

Y Gilad, M Firer, G Gellerman - Biomedicines, 2016 - mdpi.com
Targeted delivery of chemotherapeutics and diagnostic agents conjugated to carrier ligands
has made significant progress in recent years, both in regards to the structural design of the …

Peptide-based targeted therapeutics: Focus on cancer treatment

F Araste, K Abnous, M Hashemi, SM Taghdisi… - Journal of controlled …, 2018 - Elsevier
Therapeutic peptides are attracting increasing attention for biomedical applications.
Peptides present promising opportunities in targeted drug delivery due to their high …