Exosomes from adipose‐derived stem cells and application to skin wound healing

Y An, S Lin, X Tan, S Zhu, F Nie, Y Zhen, L Gu… - Cell …, 2021 - Wiley Online Library
Skin wound healing is an intractable problem that represents an urgent clinical need. To
solve this problem, a large number of studies have focused on the use of exosomes (EXOs) …

Prospective application of exosomes derived from adipose‐derived stem cells in skin wound healing: A review

H Qiu, S Liu, K Wu, R Zhao, L Cao… - Journal of cosmetic …, 2020 - Wiley Online Library
Background Wound healing has always been an intractable medical problem for both
clinicians and researchers and a burden for patients both physically and financially. Poor …

Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway

W Zhang, X Bai, B Zhao, Y Li, Y Zhang, Z Li… - Experimental cell …, 2018 - Elsevier
Introduction Adipose tissue-derived stem cells (ADSCs) have been shown to enhance
wound healing via their paracrine function. Exosomes, as one of the most important …

[HTML][HTML] Combined topical and systemic administration with human adipose-derived mesenchymal stem cells (hADSC) and hADSC-derived exosomes markedly …

Y Zhou, B Zhao, XL Zhang, Y Lu, ST Lu… - Stem cell research & …, 2021 - Springer
Background Cutaneous wound healing and regeneration have become a recognized health
challenge in the world, which causes severe damage to the mental and physical health of …

Adipose‐derived mesenchymal stem cell‐derived exosomes biopotentiated extracellular matrix hydrogels accelerate diabetic wound healing and skin regeneration

Y Song, Y You, X Xu, J Lu, X Huang, J Zhang… - Advanced …, 2023 - Wiley Online Library
Wound healing is an urgent clinical challenge, particularly in the case of chronic wounds.
Traditional approaches to wound healing have limited therapeutic efficacy due to lengthy …

[HTML][HTML] Stem cell-derived exosomes: emerging therapeutic opportunities for wound healing

C Zhou, B Zhang, Y Yang, Q Jiang, T Li, J Gong… - Stem cell research & …, 2023 - Springer
Wound healing is a dynamic and highly sequential process involving a series of overlapping
spatial and temporal phases, including hemostasis, inflammation, proliferation, and tissue …

[HTML][HTML] Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts

LI Hu, J Wang, X Zhou, Z Xiong, J Zhao, R Yu… - Scientific reports, 2016 - nature.com
Prolonged healing and scar formation are two major challenges in the treatment of soft
tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue …

[HTML][HTML] Exosomes from adipose-derived stem cells: the emerging roles and applications in tissue regeneration of plastic and cosmetic surgery

M Xiong, Q Zhang, W Hu, C Zhao, W Lv, Y Yi… - Frontiers in Cell and …, 2020 - frontiersin.org
Adipose-derived stem cells (ASCs) are an important stem cell type separated from adipose
tissue, with the properties of multilineage differentiation, easy availability, high proliferation …

Adipose mesenchymal stem cell exosomes promote wound healing through accelerated keratinocyte migration and proliferation by activating the AKT/HIF-1α axis

Y Zhang, F Han, L Gu, P Ji, X Yang, M Liu… - Journal of Molecular …, 2020 - Springer
Accelerating wound healing is a key consideration for surgeons. The three stages of wound
healing include the inflammatory response, cell proliferation and tissue repair, and much …

[HTML][HTML] Adipose mesenchymal stem cell-derived exosomes accelerate skin wound healing via the lncRNA H19/miR-19b/SOX9 axis

L Qian, L Pi, BR Fang, XX Meng - Laboratory Investigation, 2021 - Elsevier
It has been reported that adipose mesenchymal stem cells (ADSCs) accelerate wound
healing. Moreover, exosomes, which serve as paracrine factors, play a vital role in wound …