[HTML][HTML] Regulation of signal transduction pathways in colorectal cancer: implications for therapeutic resistance

Y Yeoh, TY Low, N Abu, PY Lee - PeerJ, 2021 - peerj.com
Resistance to anti-cancer treatments is a critical and widespread health issue that has
brought serious impacts on lives, the economy and public policies. Mounting research has …

[HTML][HTML] Wnt/β‑catenin signaling: Causes and treatment targets of drug resistance in colorectal cancer

GX Zhu, D Gao, ZZ Shao, L Chen… - Molecular …, 2021 - spandidos-publications.com
Colorectal cancer (CRC) is the third most common malignant tumor in humans.
Chemotherapy is used for the treatment of CRC. However, the effect of chemotherapy …

[HTML][HTML] Drug resistance in colorectal cancer: from mechanism to clinic

Q Wang, X Shen, G Chen, J Du - Cancers, 2022 - mdpi.com
Simple Summary Chemotherapy, radiotherapy and molecularly targeted therapy could
improve the prognosis of colorectal cancer (CRC) patients. Recently, immunotherapy …

[HTML][HTML] Multi drug resistance in colorectal cancer-approaches to overcome, advancements and future success

S Ashique, M Bhowmick, R Pal, H Khatoon… - Advances in Cancer …, 2024 - Elsevier
A significant obstacle to treating cancer is multidrug resistance (MDR), which is the capacity
of cancerous cells to develop resistance to both traditional and cutting-edge …

[HTML][HTML] Role of Wnt/β-Catenin Signaling in the Chemoresistance Modulation of Colorectal Cancer

S Yuan, F Tao, X Zhang, Y Zhang, X Sun… - BioMed research …, 2020 - hindawi.com
Colorectal cancer (CRC) is a common malignancy with high morbidity and mortality
worldwide. To date, chemotherapy plays an important role in the treatment of CRC patients …

[图书][B] Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies

CH Cho, T Hu - 2020 - books.google.com
Drug Resistance in Colorectal Cancer: Molecular Mechanisms and Therapeutic Strategies,
Volume Eight, summarizes the molecular mechanisms of drug resistance in colorectal …

Molecular aspects of resistance to biological and non-biological drugs and strategies to overcome resistance in colorectal cancer

T Troiani, E Martinelli, S Napolitano… - Current medicinal …, 2014 - ingentaconnect.com
A number of successful systemic therapies are available for the treatment of disseminated
cancers. However, tumor response is often transient, and therapy frequently fails due to …

Drug resistance, predictive markers and pharmacogenomics in colorectal cancer

DB Longley, WL Allen, PG Johnston - … et Biophysica Acta (BBA)-Reviews on …, 2006 - Elsevier
Resistance to chemotherapy limits the effectiveness of current cancer therapies, including
those used to treat colorectal cancer, which is the second most common cause of cancer …

Pharmacologic resistance in colorectal cancer: a review

WA Hammond, A Swaika… - Therapeutic advances in …, 2016 - journals.sagepub.com
Colorectal cancer (CRC) persists as one of the most prevalent and deadly tumor types in
both men and women worldwide. This is in spite of widespread, effective measures of …

[HTML][HTML] Molecular mechanisms targeting drug-resistance and metastasis in colorectal cancer: Updates and beyond

S Al Bitar, M El-Sabban, S Doughan… - World Journal of …, 2023 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third most diagnosed malignancy and a major leading cause
of cancer-related deaths worldwide. Despite advances in therapeutic regimens, the number …