Characteristics, management and outcomes of atypical haemolytic uraemic syndrome in kidney transplant patients: a retrospective national study

J Portoles, A Huerta, E Arjona, E Gavela… - Clinical kidney …, 2021 - academic.oup.com
Abstract Background Kidney transplantation (KTx) is a strong trigger for the development of
either recurrent or de novo atypical haemolytic uraemic syndrome (aHUS). According to …

[HTML][HTML] Eculizumab rescue therapy in patients with recurrent atypical hemolytic uremic syndrome after kidney transplantation

C Duineveld, RN Bouwmeester, KL Wijnsma… - Kidney International …, 2023 - Elsevier
Introduction Since 2016, kidney transplantation in patients with atypical hemolytic uremic
syndrome (aHUS) in the Netherlands is performed without eculizumab prophylaxis …

Atypical hemolytic uremic syndrome after kidney transplantation: lessons learned from the good, the bad, and the ugly. A case series with literature review

SA Fayek, SR Allam, E Martinez, G Pan, A Dao… - Transplantation …, 2020 - Elsevier
Atypical hemolytic uremic syndrome (aHUS) after kidney transplantation is rare and carries a
grave outcome. We present a single-center experience of all aHUS cases since the …

Outcomes of patients with atypical haemolytic uraemic syndrome with native and transplanted kidneys treated with eculizumab: a pooled post hoc analysis

CM Legendre, JM Campistol, T Feldkamp… - Transplant …, 2017 - Wiley Online Library
Atypical haemolytic uraemic syndrome (aHUS) often leads to end‐stage renal disease
(ESRD) and kidney transplantation; graft loss rates are high due to disease recurrence. A …

Kidney transplant in patients with atypical hemolytic uremic syndrome in the anti-C5 era: Single-center experience with tailored Eculizumab

G Ardissino, D Cresseri, F Tel, A Giussani… - Journal of …, 2021 - Springer
Rationale and objective Patients with atypical hemolytic uremic syndrome (aHUS) have long
been considered ineligible for kidney transplantation (KTx) in several centers due to the high …

[HTML][HTML] Eculizumab use for kidney transplantation in patients with a diagnosis of atypical hemolytic uremic syndrome

AM Siedlecki, N Isbel, JV Walle, JJ Eggleston… - Kidney International …, 2019 - Elsevier
Introduction Recurrence of atypical hemolytic uremic syndrome (aHUS) in renal allografts is
common, leading to dialysis and graft failure. Pretransplant versus posttransplant initiation of …

Midterm outcomes of 12 renal transplant recipients treated with eculizumab to prevent atypical hemolytic syndrome recurrence

C Levi, V Frémeaux-Bacchi, J Zuber, M Rabant… - …, 2017 - journals.lww.com
Background Atypical hemolytic uremic syndrome (aHUS) is an orphan disease with a high
rate of recurrence after kidney transplantation. However, reports of successful prevention of …

Living donor kidney transplantation in atypical hemolytic uremic syndrome: a case series

C Duineveld, JC Verhave, SP Berger… - American Journal of …, 2017 - Elsevier
Background The development of complement inhibitors has greatly improved the outcome of
patients with atypical hemolytic uremic syndrome (aHUS), making kidney transplantation a …

Belgian consensus statement on the diagnosis and management of patients with atypical hemolytic uremic syndrome

KJ Claes, A Massart, L Collard, L Weekers… - Acta Clinica …, 2018 - Taylor & Francis
In the last decade, significant progress has been made in the understanding and the
treatment of patients with atypical Hemolytic Uremic Syndrome (aHUS). aHUS has emerged …

[HTML][HTML] Outcomes of kidney transplant patients with atypical hemolytic uremic syndrome treated with eculizumab: a systematic review and meta-analysis

ML Gonzalez Suarez, C Thongprayoon… - Journal of Clinical …, 2019 - mdpi.com
Background: Kidney transplantation in patients with atypical hemolytic uremic syndrome
(aHUS) is frequently complicated by recurrence, resulting in thrombotic microangiopathy in …