[HTML][HTML] A review on therapeutical potential of paeonol in atherosclerosis

W Yu, I Ilyas, N Aktar, S Xu - Frontiers in Pharmacology, 2022 - frontiersin.org
The morbidity and mortality of atherosclerotic cardiovascular disease (ASCVD) is increasing
year by year. Cortex Moutan is a traditional Chinese medicinal herb that has been widely …

Beneficial effects exerted by paeonol in the management of atherosclerosis

L Lu, Y Qin, C Chen, X Guo - Oxidative medicine and cellular …, 2018 - Wiley Online Library
Atherosclerosis, a chronic luminal stenosis disorder occurred in large and medium arteries,
is the principle pathological basis of cardiovascular diseases with the highest morbidity and …

[HTML][HTML] Biological activities of paeonol in cardiovascular diseases: a review

S Vellasamy, D Murugan, R Abas, A Alias, WY Seng… - Molecules, 2021 - mdpi.com
Paeonol is a naturally existing bioactive compound found in the root bark of Paeonia
suffruticosa and it is traditionally used in Chinese medicine for the prevention and …

[HTML][HTML] Paeonol for the treatment of atherosclerotic cardiovascular disease: A pharmacological and mechanistic overview

M Wu, Z Yu, X Li, X Zhang, S Wang, S Yang… - Frontiers in …, 2021 - frontiersin.org
With improvement in living standards and average life expectancy, atherosclerotic
cardiovascular disease incidences and mortality have been increasing annually. Paeonia …

Review of the protective mechanism of Paeonol on cardiovascular disease

C Yang, J Cheng, Q Zhu, Q Pan, K Ji… - … Design, Development and …, 2023 - Taylor & Francis
Cardiovascular disease (CVD) is one of the leading causes of death in the world. Paeonol
(Pae) is a phenolic component extracted from peony bark, peony root and Xu Changqing …

Protective mechanism of Paeonol on central nervous system

R Wu, Y Liu, F Zhang, S Dai, X Xue… - Phytotherapy …, 2024 - Wiley Online Library
Cerebrovascular diseases involve neuronal damage, resulting in degenerative neuropathy
and posing a serious threat to human health. The discovery of effective drug components …

Paeonol inhibits oxidized low density lipoprotein-induced monocyte adhesion to vascular endothelial cells by inhibiting the mitogen activated protein kinase pathway

YQ Wang, M Dai, JC Zhong, DK Yin - Biological and Pharmaceutical …, 2012 - jstage.jst.go.jp
Atherosclerosis is a chronic inflammatory disease characterized by increased expression of
adhesion molecules, which contribute to monocytes adhesion to vascular endothelial cells …

Paeonol attenuates high-fat-diet-induced atherosclerosis in rabbits by anti-inflammatory activity

H Li, M Dai, W Jia - Planta medica, 2009 - thieme-connect.com
Abstract Cortex Moutan (Paeonia suffruticosa Andrews, Ranunculaceae) has several uses
in traditional medicine, such as analgesic, antipyretic, and anti-inflammatory applications …

Paeonol: pharmacological effects and mechanisms of action

L Zhang, D Li, L Liu - International Immunopharmacology, 2019 - Elsevier
Paeonia suffruticosa possesses various medicinal benefits and has been used extensively
in traditional oriental medicine for thousands of years. Paeonol is the main component …

Paeonol Inhibits Proliferation of Vascular Smooth Muscle Cells Stimulated by High Glucose via Ras‐Raf‐ERK1/2 Signaling Pathway in Coculture Model

J Chen, M Dai, Y Wang - Evidence‐Based Complementary and …, 2014 - Wiley Online Library
Paeonol (Pae) has been previously reported to protect against atherosclerosis (AS) by
inhibiting vascular smooth muscle cell (VSMC) proliferation or vascular endothelial cell …