Background In the past 20 years, the number of adults with diabetes has tripled. For most of
the researches are often conducted in rodent T2DM models, and effective drugs developed …

In the past twenty years, the number of adults with diabetes has tripled. Most studies have
been conducted using rodent models of type 2 diabetes mellitus (T2DM), and the developed …

Objective To establish type 2 diabetes mellitus (T2DM) KM mouse models via the combined
use of high-calorie diet and multiple administration of low-dose streptozotocin (STZ) …

Type 2 diabetes is a major risk factor of the development of atherosclerosis in humans.
However, studies examining mechanisms underlying diabetes‐accelerated atherosclerosis …

The establishment of rat models of type 2 diabetes mellitus can provide an ideal animal
experimental technology platform for the research of pathogenesis, prevention, diagnosis …

Aim A stable induced type 2 diabetes model (T2DM) still needs to be explored for basic and
clinical research, due to nonuniform model methods and unstable consequences. Our aims …

Introduction: Diabetes is a chronic metabolic disease with high prevalence characterized by
hyperglycemia due to relative deficiency or lack of insulin. Type 1 Diabetes (destruction of …

Diabetes mellitus, especially type 2 diabetes (T2DM), is one of the most common chronic
diseases and continues to increase in numbers with large proportion of health care budget …

Type 1 diabetes mellitus (T1DM) is a chronic disease represented by insulin‐causing
pancreatic β‐cell disruption and hyperglycemia. Therefore, it is necessary to establish a …

Background: The previously established methods for type 2 diabetes (T2D) have mainly
concentrated on overt diabetes model development. Here, our intention was to create an …