The effect of urine-derived stem cells expressing VEGF loaded in collagen hydrogels on myogenesis and innervation following after subcutaneous implantation in …

G Liu, X Wang, X Sun, C Deng, A Atala, Y Zhang - Biomaterials, 2013 - Elsevier
Impairment of sphincter muscles or their neural and vascular support leads to stress urinary
incontinence. The aim of this study was to determine the role of urine-derived stem cells …

Skeletal myogenic differentiation of urine-derived stem cells and angiogenesis using microbeads loaded with growth factors

G Liu, RA Pareta, R Wu, Y Shi, X Zhou, H Liu, C Deng… - Biomaterials, 2013 - Elsevier
To provide site-specific delivery and targeted release of growth factors to implanted urine-
derived stem cells (USCs), we prepared microbeads of alginate containing growth factors …

A cocktail of growth factors released from a heparin hyaluronic-acid hydrogel promotes the myogenic potential of human urine-derived stem cells in vivo

G Liu, R Wu, B Yang, Y Shi, C Deng, A Atala, S Mou… - Acta biomaterialia, 2020 - Elsevier
Traditional cell therapy technology relies on the maximum expansion of primary stem cells in
vitro, through multiple passages and potential differentiation protocols, in order to generate …

Implantation of autologous urine derived stem cells expressing vascular endothelial growth factor for potential use in genitourinary reconstruction

S Wu, Z Wang, S Bharadwaj, SJ Hodges… - The Journal of …, 2011 - auajournals.org
Purpose: We evaluated the effects of vascular endothelial growth factor overexpression on
urine derived stem cell survival and myogenic differentiation to determine whether these …

Ureter tissue engineering with vessel extracellular matrix and differentiated urine-derived stem cells

Z Zhao, D Liu, Y Chen, Q Kong, D Li, Q Zhang, C Liu… - Acta biomaterialia, 2019 - Elsevier
Objective To assess the possibility of ureter tissue engineering using vessel extracellular
matrix (VECM) and differentiated urine-derived stem cells (USCs) in a rabbit model. Methods …

[HTML][HTML] Transplantation of muscle-derived stem cells plus biodegradable fibrin glue restores the urethral sphincter in a pudendal nerve-transected rat model

Y Xu, YF Song, ZX Lin - Brazilian Journal of Medical and Biological …, 2010 - SciELO Brasil
We investigated whether fibrin glue (FG) could promote urethral sphincter restoration in
muscle-derived stem cell (MDSC)-based injection therapies in a pudendal nerve-transected …

Persistence and survival of autologous muscle derived cells versus bovine collagen as potential treatment of stress urinary incontinence

T Yokoyama, N Yoshimura, R Dhir, Z QU… - The Journal of …, 2001 - Elsevier
PURPOSE: We explored the use of autologous muscle derived cells as a method of treating
stress urinary incontinence. We determined whether urethral muscle derived cell injection is …

Experimental study of therapy of bone marrow mesenchymal stem cells or muscle‐like cells/calcium alginate composite gel for the treatment of stress urinary …

XW Du, HL Wu, YF Zhu, JB Hu, F Jin… - Neurourology and …, 2013 - Wiley Online Library
Objective To explore the myoblast formation around the urethra and increase in urethral
resistance of bone marrow mesenchymal stem cells or muscle‐like cells/calcium alginate …

Differentiation of human endometrial stem cells into urothelial cells on a three‐dimensional nanofibrous silk–collagen scaffold: an autologous cell resource for …

A Shoae‐Hassani… - Journal of tissue …, 2015 - Wiley Online Library
Reconstruction of the bladder wall via in vitro differentiated stem cells on an appropriate
scaffold could be used in such conditions as cancer and neurogenic urinary bladder. This …

Tissue engineering of urethra using human vascular endothelial growth factor gene‐modified bladder urothelial cells

Y Guan, L Ou, G Hu, H Wang, Y Xu, J Chen… - Artificial …, 2008 - Wiley Online Library
Acquired or congenital abnormalities may lead to urethral damage or loss, often requiring
surgical reconstruction. Urethrocutaneous fistula and strictures are common complications …