Hepatitis C virus (HCV) infection develops into chronic hepatitis in over two-thirds of acute
infections. While current treatments with direct-acting antivirals (DAAs) achieve HCV …

Viruses must continually adapt against dynamic innate and adaptive responses of the host
immune system to establish chronic infection. Only a small minority (~ 20%) of those …

HCV infection is an exponentially growing health burden worldwide, with an estimated 170
million people infected. Although therapies for HCV are continually improving, there remain …

Natural killer cells (NK s) are involved in every stage of hepatitis C viral (HCV) infection, from
protection against HCV acquisition and resolution in the acute phase to treatment‐induced …

Hepatitis C virus (HCV) infects over 170 million people in the world. While a minority of
individuals are able to naturally clear this hepatotropic virus using their immune system …

Host defense against invading pathogens within the liver is dominated by innate immunity.
Natural killer (NK) cells have been implicated at all stages of hepatitis C virus (HCV) …

BACKGROUND & AIMS: Natural killer (NK) cells are essential early after infection, not only
for viral containment but also for timely and efficient induction of adaptive responses. An …

Hepatitis C virus (HCV) infection induces the long-term risk of liver cirrhosis or
hepatocellular carcinoma and in adults represents the most common cause of liver …

Eur J Clin Invest 2010; 40 (9): 851–863 Abstract Background Hepatitis B virus (HBV) and
hepatitis C virus (HCV) are major human hepatotropic pathogens responsible for a large …

Innate CD56pos natural killer (NK) and natural T (NT) cells comprise important hepatic
antiviral effector lymphocytes whose activity is fine-tuned through surface NK receptors …