Background Betulinic acid (BA) is a novel antineoplastic agent under evaluation for tumor
therapy. Because of the selective cytotoxic effects of BA in tumor cells (including gliomas) …

Neuroblastoma has long been recognized to show spontaneous regression during fetal
development and in the majority of stage 4s infants< 1 year of age with disseminated …

We identified betulinic acid (BetA) as a new cytotoxic agent active against neuroectodermal
tumor cells including neuroblastoma, medulloblastoma, glioblastoma and Ewing's sarcoma …

Betulinic acid (BA), a pentacyclic triterpene, represents a new therapeutic substance that
has potential benefits for treating glioblastoma. Recently, new strategies for producing BA …

Background and Purpose: Betulinic acid, a pentacyclic triterpene, is a new cytotoxic
compound active on melanoma, neuroblastoma, glioblastoma and head and neck …

Malignant brain tumors are the most common solid tumors in children. The overall prognosis
for this group of patients is still poor, emphasizing the importance of more effective therapies …

Betulinic acid (BA), a lupane-type pentacyclic triterpenoid saponin from tree bark, has the
potential to induce the apoptosis of cancer cells without toxicity towards normal cells in vitro …

Betulinic acid and betulin show promising activity against cancers cells, but the mechanism
of their action is still unclear. In this study, non-small cell lung cancer (NSCLC) cell lines …

Background Betulin, a natural pentacyclic triterpene with the lupane structure that is present
in significant amounts in the outer bark of birch, is known for its broad array of biological and …