Risk factors for a first thrombotic event in antiphospholipid antibody carriers. A multicentre, retrospective follow-up study

A Ruffatti, T Del Ross, M Ciprian, M Nuzzo… - Annals of the …, 2009 - ard.bmj.com
Objectives: To asses risk factors for a first thrombotic event in antiphospholipid antibody
(aPL) positive carriers and evaluate the efficacy of prophylactic treatments. Methods …

[HTML][HTML] The ABCs of antiphospholipid syndrome

ABK Dinçer, D Erkan - Archives of Rheumatology, 2023 - ncbi.nlm.nih.gov
Antiphospholipid syndrome (APS) is a thromboinflammatory syndrome characterized by
thrombotic, microvascular, obstetric, or non-thrombotic events in the setting of persistent …

Closing the serological gap in the antiphospholipid syndrome: the value of “non-criteria” antiphospholipid antibodies

N Zohoury, ML Bertolaccini… - The Journal of …, 2017 - jrheum.org
Objective. Most clinicians use the 2006 Sydney classification criteria to evaluate patients
suspected of having antiphospholipid syndrome (APS). Although sensitive and specific for …

Antigen specificity and clinical relevance of antiphospholipid syndrome-related autoantibodies

RR Forastiero, ME Martinuzzo - Current Rheumatology …, 2005 - ingentaconnect.com
The presence of antiphospholipid antibodies (aPL) combined with venous or arterial
thrombosis, and/or obstetric complications defines the antiphospholipid syndrome (APS) …

A pilot open‐label phase II trial of rituximab for non‐criteria manifestations of antiphospholipid syndrome

D Erkan, JA Vega, G Ramón, E Kozora… - Arthritis & …, 2013 - Wiley Online Library
Objective The primary objective of this study was to evaluate the safety of rituximab in
antiphospholipid antibody (aPL)–positive patients with non‐criteria manifestations of …

Clinical Characterization of Antiphospholipid Syndrome by Detection of IgG Antibodies Against β2‐Glycoprotein I Domain 1 and Domain 4/5: Ratio of Anti–Domain 1 …

L Andreoli, CB Chighizola, C Nalli… - Arthritis & …, 2015 - Wiley Online Library
Objective It has been suggested that only antibodies against domain 1 (D1) of β2‐
glycoprotein I (β2GPI) are pathogenic and diagnostic. The role of antibodies against other …

Prevalence, persistence and clinical correlations of classic and novel antiphospholipid antibodies in systemic lupus erythematosus

T Marchetti, C Ribi, T Perneger… - …, 2018 - academic.oup.com
Objectives aPL are frequently present in SLE. In a well characterized SLE cohort we aimed
at investigating the prevalence of aPL and assessing their analytical performance and …

Profiles of criteria and non-criteria anti-phospholipid autoantibodies are associated with clinical phenotypes of the antiphospholipid syndrome

I Volkov, L Seguro, EP Leon, L Kovács… - Autoimmunity …, 2020 - Springer
Background Specific anti-phospholipids antibodies (aPLs) are used as classification criteria
of the antiphospholipid syndrome (APS). These aPLs, although essential for diagnosis, do …

Fluctuation of Anti–Domain 1 and Anti–β2‐Glycoprotein I Antibody Titers Over Time in Patients With Persistently Positive Antiphospholipid Antibodies

CB Chighizola, F Pregnolato, D Andrade… - Arthritis & …, 2023 - Wiley Online Library
Objective The present study was undertaken to longitudinally evaluate titers of antibodies
against β2‐glycoprotein I (anti‐β2GPI) and domain 1 (anti‐D1), to identify predictors of …

Insights into the diagnosis and pathogenesis of the antiphospholipid syndrome

MHA Noureldine, W Nour-Eldine… - Seminars in Arthritis and …, 2019 - Elsevier
The Antiphospholipid syndrome (APS), formerly known as Anticardiolipin or Hughes
syndrome, is a systemic autoimmune disorder characterized by obstetrical complications …