Hereditary and inflammatory bowel disease-related early onset colorectal cancer have unique characteristics and clinical course compared with sporadic disease

AA Arif, D Chahal, GK Ladua, E Bhang, B Salh… - … Biomarkers & Prevention, 2021 - AACR
Background: Early onset colorectal cancer (EoCRC), diagnosed in those< 50 years old, is
increasing in incidence. We sought to differentiate characteristics and outcomes of EoCRC …

Advances in Understanding Early-Onset Colorectal Cancer

RB Hayes - Cancer Epidemiology, Biomarkers & Prevention, 2021 - AACR
Since the 1990s, the incidence of early-onset colorectal cancer (at< 50 years of age) in the
US has increased by more than 50%; similar increases have also been observed …

Risk factors and clinical characteristics of early-onset colorectal cancer vs. late-onset colorectal cancer: a case-case study

M Di Leo, RA Zuppardo, M Puzzono… - European Journal of …, 2021 - journals.lww.com
Methods In this retrospective case-case study, patients were prospectively enrolled from
2015 to 2018. We collected clinical features (age, sex, time from symptom onset to …

Young age of onset colorectal cancers

J Liang, MF Kalady, J Church - International journal of colorectal disease, 2015 - Springer
Background Colorectal cancer is typically a condition of older patients with only 10%
diagnosed under the age of 50 years. Often, diagnosis is delayed, but certain factors such as …

A comprehensive comparison of early-onset and average-onset colorectal cancers

A Cercek, WK Chatila, R Yaeger… - JNCI: Journal of the …, 2021 - academic.oup.com
Background The causative factors for the recent increase in early-onset colorectal cancer
(EO-CRC) incidence are unknown. We sought to determine if early-onset disease is …

Hereditary colorectal cancer syndromes and inflammatory bowel diseases: An ECCO CONFER multicentre case series

B Barberio, E Savarino, B Verstockt… - Journal of Crohn's …, 2022 - academic.oup.com
Background Hereditary colorectal cancer syndromes [HCCS] are rare polyposis or
nonpolyposis syndromes with a higher risk of developing colorectal cancer [CRC] …

[HTML][HTML] Early-onset colorectal cancer: a sporadic or inherited disease?

V Stigliano, L Sanchez-Mete, A Martayan… - World journal of …, 2014 - ncbi.nlm.nih.gov
Colorectal cancer is the third most common cancer diagnosed worldwide. Although
epidemiology data show a marked variability around the world, its overall incidence rate …

Comprehensive Analysis of Early-onset Colorectal Cancer: A Review

K Takada, K Hotta, Y Kishida, S Ito, K Imai… - Journal of the Anus …, 2023 - jstage.jst.go.jp
Early-onset colorectal cancer (CRC), which refers to CRC diagnosed in individuals below
the age of 50 years, is a growing health concern that presents unique challenges in …

[HTML][HTML] The inherited and familial component of early-onset colorectal cancer

M Daca Alvarez, I Quintana, M Terradas, P Mur… - Cells, 2021 - mdpi.com
Early-onset colorectal cancer (EOCRC), defined as that diagnosed before the age of 50,
accounts for 10–12% of all new colorectal cancer (CRC) diagnoses. Epidemiological data …

[HTML][HTML] Different Oncologic Outcomes in Early-Onset and Late-Onset Sporadic Colorectal Cancer: A Regression Analysis on 2073 Patients

C Foppa, A Maroli, S Lauricella, A Luberto, C La Raja… - Cancers, 2022 - mdpi.com
Simple Summary Early-onset colorectal cancer (EOCRC) is on the rise. Reasons are
unknown and comparative results about long-term survival are still widely debated. This …