Rising incidence of early-onset colorectal cancer—A call to action

N Akimoto, T Ugai, R Zhong, T Hamada… - Nature reviews Clinical …, 2021 - nature.com
The incidence of early-onset colorectal cancer (CRC), which occurs in individuals< 50 years
of age, has been increasing worldwide and particularly in high-income countries. The …

Early-onset colorectal cancer

MA Jeong, HW Kang - The Korean Journal of …, 2019 - synapse.koreamed.org
The incidence of colorectal cancer (CRC) is increasing among young adults in several
countries including the United States. Early-onset colorectal cancer (EO-CRC) is …

[HTML][HTML] Clinical and molecular features of young-onset colorectal cancer

V Ballester, S Rashtak, L Boardman - World journal of …, 2016 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the leading causes of cancer related mortality worldwide.
Although young-onset CRC raises the possibility of a hereditary component, hereditary CRC …

[HTML][HTML] Distinct molecular profiles of sporadic early-onset colorectal cancer: a population-based cohort and systematic review

AC Hamilton, FJ Bannon, PD Dunne, J James… - Gastro Hep …, 2023 - Elsevier
Background and Aims The observed increase in the incidence of early-onset colorectal
cancer (EOCRC) is being driven by sporadic cases, but the molecular characteristics of …

A high percentage of early-age onset colorectal cancer is potentially preventable

PP Stanich, KR Pelstring, H Hampel… - Gastroenterology, 2021 - gastrojournal.org
Results The OCCPI included 713 patients with EAOCRC who met inclusion criteria: 566
patients (79.4%) without a family history or identified hereditary cancer syndrome, 64 (9.0%) …

Family history as a risk factor for colorectal cancer in inflammatory bowel disease

J Askling, PW Dickman, A Ekbom, P Karlén, O Broström… - Gastroenterology, 2001 - Elsevier
Background & Aims: Familial colorectal cancer (CRC) is a risk factor for CRC in healthy
individuals and, as indicated by case-control studies, possibly in ulcerative colitis. Little is …

Early-onset colorectal cancer: current insights

F Ullah, AB Pillai, N Omar, D Dima, S Harichand - Cancers, 2023 - mdpi.com
Simple Summary Early-onset colorectal cancer is increasing in incidence in the United
States, and it is expected to more than double in the next 10 years. There are many risk …

[HTML][HTML] Assessing presenting symptoms, co-morbidities, and risk factors for mortality in underserved patients with non-hereditary early-onset colorectal cancer

S Reddy, A Mouchli, L Bierle, M Gerrard, C Walsh… - Cureus, 2021 - ncbi.nlm.nih.gov
Background The presenting symptoms and co-morbidities contributing to mortality in young
patients (age< 50 years old) with colorectal cancer (CRC) are poorly understood. We …

The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection

SG Patel, JJ Karlitz, T Yen, CH Lieu… - The lancet …, 2022 - thelancet.com
The incidence of early-onset colorectal—ie, colorectal cancer cancer diagnosed in patients
under the age of 50 years—has been increasing around the world. This Series paper …

Early-onset colorectal cancer is associated with a lower risk of metachronous advanced neoplasia than traditional-onset colorectal cancer

FW Chen, L Yang, VT Cusumano, MC Chong… - Digestive Diseases and …, 2022 - Springer
Background Colorectal cancer (CRC) incidence in the USA has increased in adults under
age 50. Current CRC surveillance guidelines do not consider age at diagnosis, and there …