[HTML][HTML] Widespread resistance mutations to sulfadoxine-pyrimethamine in malaria parasites imported to China from Central and Western Africa

L Zhao, L Pi, Y Qin, Y Lu, W Zeng, Z Xiang, P Qin… - International Journal for …, 2020 - Elsevier
Background Imported cases of infectious disease provide invaluable information about
epidemiological conditions abroad, and should guide treatment decisions at home and …

Molecular surveillance of anti-malarial resistance Pfdhfr and Pfdhps polymorphisms in African and Southeast Asia Plasmodium falciparum imported parasites to …

T Jiang, W Cheng, Y Yao, H Tan, K Wu, J Li - Malaria Journal, 2020 - Springer
Background Anti-malarial drug resistance is a severe challenge for eventual control and
global elimination of malaria. Resistance to sulfadoxine-pyrimethamine (SP) increases as …

Mutation Profile of pfdhfr and pfdhps in Plasmodium falciparum among Returned Chinese Migrant Workers from Africa

C Xu, H Sun, Q Wei, J Li, T Xiao, X Kong… - Antimicrobial Agents …, 2019 - Am Soc Microbiol
We evaluated markers of sulfadoxine-pyrimethamine (SP) resistance in Plasmodium
falciparum among 254 returned migrant workers in China from Africa from 2013 to 2016 …

Low-grade sulfadoxine–pyrimethamine resistance in Plasmodium falciparum parasites from Lubango, Angola

EPS Kaingona-Daniel, LR Gomes, BE Gama… - Malaria Journal, 2016 - Springer
Background Malaria is a major parasitic disease, affecting millions of people in endemic
areas. Plasmodium falciparum parasites are responsible for the most severe cases and its …

Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi

M Ravenhall, ED Benavente, M Mipando, ATR Jensen… - Malaria journal, 2016 - Springer
Background Malawi experienced prolonged use of sulfadoxine/pyrimethamine (SP) as the
front-line anti-malarial drug, with early replacement of chloroquine and delayed introduction …

Markers of sulfadoxine–pyrimethamine resistance in Eastern Democratic Republic of Congo; implications for malaria chemoprevention

M van Lenthe, R van Der Meulen, M Lassovski… - Malaria journal, 2019 - Springer
Background Sulfadoxine–pyrimethamine (SP) is a cornerstone of malaria chemoprophylaxis
and is considered for programmes in the Democratic Republic of Congo (DRC). However …

Geographical spread and structural basis of sulfadoxine-pyrimethamine drug-resistant malaria parasites

R Chaturvedi, J Chhibber-Goel, I Verma… - International Journal for …, 2021 - Elsevier
The global spread of sulfadoxine (Sdx, S) and pyrimethamine (Pyr, P) resistance is attributed
to increasing number of mutations in DHPS and DHFR enzymes encoded by malaria …

Origins and spread of novel genetic variants of sulfadoxine–pyrimethamine resistance in Plasmodium falciparum isolates in Indonesia

S Basuki, Fitriah, PM Risamasu, Kasmijati, P Ariami… - Malaria Journal, 2018 - Springer
Background While malaria incidence in Indonesia has decreased threefold in the last
decade, more than 200,000 cases were reported in 2016. Different endemicity of …

[HTML][HTML] High Frequency Mutations in pfdhfr and pfdhps of Plasmodium falciparum in Response to Sulfadoxine-Pyrimethamine: A Cross-Sectional Survey in …

H Yan, J Feng, J Yin, F Huang, X Kong, K Lin… - Frontiers in Cellular …, 2021 - frontiersin.org
Background Sulfadoxine-pyrimethamine (SP) is recommended for intermittent preventive
treatment in Africa against Plasmodium falciparum infection. However, increasing SP …

Temporal evolution of sulfadoxine-pyrimethamine resistance genotypes and genetic diversity in response to a decade of increased interventions against Plasmodium …

LN Amenga-Etego, V Asoala, G Agongo, C Jacob… - Malaria Journal, 2021 - Springer
Background Anti-malarial drug resistance remains a key concern for the global fight against
malaria. In Ghana sulfadoxine-pyrimethamine (SP) is used for intermittent preventive …