A mechanistic model on the role of “radially-running” collagen fibers on dissection properties of human ascending thoracic aorta
Aortic dissection (AoD) is a common condition that often leads to life-threatening
cardiovascular emergency. From a biomechanics viewpoint, AoD involves failure of load …
cardiovascular emergency. From a biomechanics viewpoint, AoD involves failure of load …
Structural modeling reveals microstructure-strength relationship for human ascending thoracic aorta
High lethality of aortic dissection necessitates accurate predictive metrics for dissection risk
assessment. The not infrequent incidence of dissection at aortic diameters< 5.5 cm, the …
assessment. The not infrequent incidence of dissection at aortic diameters< 5.5 cm, the …
Differential propensity of dissection along the aorta
E Ban, C Cavinato, JD Humphrey - Biomechanics and modeling in …, 2021 - Springer
Aortic dissections progress, in part, by delamination of the wall. Previous experiments on cut-
open segments of aorta demonstrated that fluid injected within the wall delaminates the …
open segments of aorta demonstrated that fluid injected within the wall delaminates the …
Effect of aneurysm on biomechanical properties of “radially-oriented” collagen fibers in human ascending thoracic aortic media
We recently reported a mechanistic model to link micro-architectural information to the
delamination strength (S d) of human ascending thoracic aorta (ATA). That analysis …
delamination strength (S d) of human ascending thoracic aorta (ATA). That analysis …
Critical pressure of intramural delamination in aortic dissection
E Ban, C Cavinato, JD Humphrey - Annals of biomedical engineering, 2022 - Springer
Computational models of aortic dissection can examine mechanisms by which this
potentially lethal condition develops and propagates. We present results from phase-field …
potentially lethal condition develops and propagates. We present results from phase-field …
Multimodality imaging-based characterization of regional material properties in a murine model of aortic dissection
MR Bersi, VA Acosta Santamaría, K Marback… - Scientific reports, 2020 - nature.com
Chronic infusion of angiotensin-II in atheroprone (ApoE−/−) mice provides a reproducible
model of dissection in the suprarenal abdominal aorta, often with a false lumen and …
model of dissection in the suprarenal abdominal aorta, often with a false lumen and …
Review of current advances in the mechanical description and quantification of aortic dissection mechanisms
Aortic dissection is a life-threatening event associated with a very poor outcome. A number
of complex phenomena are involved in the initiation and propagation of the disease …
of complex phenomena are involved in the initiation and propagation of the disease …
Biomechanical roles of medial pooling of glycosaminoglycans in thoracic aortic dissection
S Roccabianca, GA Ateshian, JD Humphrey - Biomechanics and modeling …, 2014 - Springer
Spontaneous dissection of the human thoracic aorta is responsible for significant morbidity
and mortality, yet this devastating biomechanical failure process remains poorly understood …
and mortality, yet this devastating biomechanical failure process remains poorly understood …
Regional delamination strength in the human aorta underlies the anatomical localization of the dissection channel
DP Sokolis, SA Papadodima - Journal of Biomechanics, 2022 - Elsevier
Aortic dissection is a life-threatening event, during which a primary tear propagates along
the aorta causing catastrophic delamination of the inner (intima with most of the media) from …
the aorta causing catastrophic delamination of the inner (intima with most of the media) from …
Avalanches and power law behavior in aortic dissection propagation
Aortic dissection is a devastating cardiovascular disease known for its rapid propagation
and high morbidity and mortality. The mechanisms underlying the propagation of aortic …
and high morbidity and mortality. The mechanisms underlying the propagation of aortic …
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