Background Complement activation in atypical hemolytic uremic syndrome (aHUS), C3
glomerulonephropathy (C3G) and immune complex-mediated membranoproliferative …

Atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G) have been
linked to mutations in many of the proteins that are involved in alternative complement …

Over recent years, complement has emerged as a major player in the development of a
number of glomerular diseases, including atypical haemolytic uraemic syndrome …

C3 glomerulopathy (C3G) and atypical hemolytic uremic syndrome (aHUS) are two rare
diseases caused by dysregulated activity of the alternative pathway of complement …

Atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G) are associated
with dysregulation and overactivation of the complement alternative pathway. Typically …

Atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G) are associated
with loss of regulation of the alternative pathway of complement and its resulting …

The spectrum of immune-mediated glomerular diseases is wide, ranging from rare diseases
with well-recognized genetic origins to more common and multifactorial diseases. Immune …

Despite distinct renal lesions, a series of rare glomerular nephropathies are reportedly
mediated by complement overactivation. Genetic variations in complement genes contribute …

Interventions: Screenings for genetic mutations contributed to complement system
dysregulation were performed on patient II-1. Outcomes: The genome sequencing identified …

Complement‐mediated atypical hemolytic uremic syndrome (aHUS) is an ultra‐rare renal
disease primarily caused by genetic alterations in complement proteins. The genetic work …