Aims: This study was aimed to formulate erlotinib (ERL)-loaded transferosomal gel (ERL@
TG) intended for topical application for the treatment of ductal carcinoma in situ. Materials & …

Letrozole (LTZ) is used as first-line treatment for hormone-positive breast cancer (BC) in
postmenopausal women. However, its poor aqueous solubility and permeability have …

Objective Itraconazole (ITZ), a widely used systemic antifungal drug, has been ingeniously
repurposed for its antitumor effects. In the present work, we have prepared and optimized …

The present study was designed to engineer surface-anchored and methotrexate loaded
lipobrid nano-constructs for targeting breast cancer. Ligands (fucose, galactose and …

Purpose Letrozole as a steroidal anticancer drug with hydrophobic nature is usually
administrated by oral route for patient treatment and the injectable formulation for this drug …

Objective: The goal of this study is to use Design Expert Software to evaluate a
transfersomal gel formulation for transdermal administration of Methotrexate utilising the …

Purpose: In this study, we report the design, development and evaluation of a hollow drug
delivery nanoplatform for cancer therapy in vitro and in vivo. This composite nanosystem …

While the treatment regimen of certain types of breast cancer involves a combination of
hormonal therapy and chemotherapy, the outcomes are limited due to the difference in the …

Background Topical anticancer drugs offer a potential therapeutic modality with high
compliance for treating cutaneous squamous cell carcinoma (cSCC). However, the existing …

Localized drug delivery to the breast tissues is an area of interest as a potential route to
ensure site-specific drug delivery. Transpapillary delivery via the mammary papilla has …