August Krogh's theory of muscle microvascular control and oxygen delivery: a paradigm shift based on new data
August Krogh twice won the prestigious international Steegen Prize, for nitrogen metabolism
(1906) and overturning the concept of active transport of gases across the pulmonary …
(1906) and overturning the concept of active transport of gases across the pulmonary …
[PDF][PDF] Skeletal muscle: microcirculatory adaptation to metabolic demand
RT Hepple - Medicine and science in sports and exercise, 2000 - researchgate.net
ABSTRACT HEPPLE, RT Skeletal muscle: microcirculatory adaptation to metabolic demand.
Med. Sci. Sports Exerc., Vol. 32, No. 1, pp. 117–123, 2000. The issue of whether skeletal …
Med. Sci. Sports Exerc., Vol. 32, No. 1, pp. 117–123, 2000. The issue of whether skeletal …
Bioengineering analysis of blood flow in resting skeletal muscle
GW Schmid-Schönbein, TC Skalak… - … hemodynamics of systemic …, 1989 - Springer
Blood flow in skeletal muscle serves to supply nutrients to the muscle fibers and to remove
metabolites; it controls tissue growth and atrophy, and determines the response of muscle in …
metabolites; it controls tissue growth and atrophy, and determines the response of muscle in …
The importance of capillary distribution in supporting muscle function, building on Krogh's seminal ideas
Krogh's Nobel prize for insightful studies into the physiology of capillaries heralded a
revolution in understanding that continues today. The view of passive conduits has been …
revolution in understanding that continues today. The view of passive conduits has been …
The role of the microcirculation in muscle function and plasticity
P Hendrickse, H Degens - Journal of Muscle Research and Cell Motility, 2019 - Springer
It is widely acknowledged that maintenance of muscle, size, strength and endurance is
necessary for quality of life and the role that skeletal muscle microcirculation plays in muscle …
necessary for quality of life and the role that skeletal muscle microcirculation plays in muscle …
[PDF][PDF] Dynamics of muscle microcirculatory oxygen exchange
ABSTRACT POOLE, DC, BJ BEHNKE, and DJ PADILLA. Dynamics of Muscle
Microcirculatory Oxygen Exchange. Med. Sci. Sports Exerc., Vol. 37, No. 9, pp. 1559–1566 …
Microcirculatory Oxygen Exchange. Med. Sci. Sports Exerc., Vol. 37, No. 9, pp. 1559–1566 …
Krogh's capillary recruitment hypothesis, 100 years on: Is the opening of previously closed capillaries necessary to ensure muscle oxygenation during exercise?
H Angleys, L Østergaard - American Journal of Physiology …, 2020 - journals.physiology.org
In 1919, August Krogh published his seminal work on skeletal muscle oxygenation. Krogh's
observations indicated that muscle capillary diameter is actively regulated, rather than a …
observations indicated that muscle capillary diameter is actively regulated, rather than a …
Capillary endothelial cells as coordinators of skeletal muscle blood flow during active hyperemia
CL Murrant, IR Lamb, NM Novielli - Microcirculation, 2017 - Wiley Online Library
In this invited review, we explore the burgeoning possibility of capillary endothelial cells as
coordinators of skeletal muscle blood flow in response to muscle contraction. The idea that …
coordinators of skeletal muscle blood flow in response to muscle contraction. The idea that …
Control of oxygen uptake during exercise.
DC Poole, TJ Barstow, P McDonough… - Medicine and science …, 2008 - europepmc.org
Other than during sleep and contrived laboratory testing protocols, humans rarely exist in
prolonged metabolic steady states; rather, they transition among different metabolic rates (V …
prolonged metabolic steady states; rather, they transition among different metabolic rates (V …
Capillary hemodynamics and oxygen pressures in the aging microcirculation
Healthy aging acts to redistribute blood flow (Q˙) and thus O2 delivery (Q˙ O2) among and
within the exercising muscles such that Q˙ O2 to highly oxidative muscle fibers may be …
within the exercising muscles such that Q˙ O2 to highly oxidative muscle fibers may be …