National and international guidelines still recommend β-blockers (BBs) as first-line agents in
uncomplicated prevention of hypertension. However, it has been shown that BBs reduce …

In the past 4 decades, β blockers (BBs) have been widely used in the treatment of
uncomplicated hypertension and are still recommended as first-line agents in national and …

Introduction International guidelines have removed b-blockers from first-line treatment of
hypertension, limiting their use to patients with compelling indications. The position of …

For more than 3 decades, beta-blockers have been widely used in the treatment of
hypertension and are still recommended as first-line agents by national and international …

Some national guidelines on hypertension have demoted beta-blockers from a first-choice to
a fourth-choice treatment. In contrast, the 2007 guidelines of the European Society of …

Beta-blockers have long being used as first-line therapy for hypertension as their use had
resulted in a reduction in cardiovascular morbidity and mortality in controlled clinical trials. A …

Background: Meta-analyses from randomized outcome-based trials have challenged the
role of beta-blockers for the treatment of hypertension. However, because they often include …

β-Blockers are used commonly worldwide in clinical practice for lowering blood pressure.
Most of the agents in this class are efficacious in reducing blood pressure, although they …

Objective: This review covers the pharmacokinetics and pharmacodynamic of β-blockers,
the rationale for their use, some recent controversies in its use for managing hypertension …

Importance of the field: It is important to know which patients with hypertension will benefit
from beta-blocker therapy and which beta-blockers should be used in the treatment of …