[HTML][HTML] Microvesicles from human adipose stem cells promote wound healing by optimizing cellular functions via AKT and ERK signaling pathways

S Ren, J Chen, D Duscher, Y Liu, G Guo… - Stem Cell Research & …, 2019 - Springer
Background Human adipose stem cells (ASCs) have emerged as a promising treatment
paradigm for skin wounds. Recent works demonstrate that the therapeutic effect of stem cells …

Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway

W Zhang, X Bai, B Zhao, Y Li, Y Zhang, Z Li… - Experimental cell …, 2018 - Elsevier
Introduction Adipose tissue-derived stem cells (ADSCs) have been shown to enhance
wound healing via their paracrine function. Exosomes, as one of the most important …

Extracellular vesicle‐enclosed miR‐486‐5p mediates wound healing with adipose‐derived stem cells by promoting angiogenesis

Y Lu, H Wen, J Huang, P Liao, H Liao… - Journal of Cellular …, 2020 - Wiley Online Library
Adipose‐derived stem cells (ASC) are said to have a pivotal role in wound healing.
Specifically, ASC‐secreted extracellular vesicles (EV) carry diverse cargos such as …

Locally administered adipose-derived stem cells accelerate wound healing through differentiation and vasculogenesis

C Nie, D Yang, J Xu, Z Si, X Jin… - Cell …, 2011 - journals.sagepub.com
Despite advances in wound closure techniques and devices, there is still a critical need for
new methods of enhancing the healing process to achieve optimal outcomes. Recently …

[HTML][HTML] Exosomes derived from human adipose mensenchymal stem cells accelerates cutaneous wound healing via optimizing the characteristics of fibroblasts

LI Hu, J Wang, X Zhou, Z Xiong, J Zhao, R Yu… - Scientific reports, 2016 - nature.com
Prolonged healing and scar formation are two major challenges in the treatment of soft
tissue trauma. Adipose mesenchymal stem cells (ASCs) play an important role in tissue …

Self‐assembled adult adipose‐derived stem cell spheroids combined with biomaterials promote wound healing in a rat skin repair model

S Hsu, PS Hsieh - Wound Repair and Regeneration, 2015 - Wiley Online Library
Adult adipose‐derived stem cells (ASC s) are a type of multipotent mesenchymal stem cells
(MSC s) with easy availability and serve as a potential cell source for cell‐based therapy …

[HTML][HTML] Exosomes secreted by human adipose mesenchymal stem cells promote scarless cutaneous repair by regulating extracellular matrix remodelling

L Wang, L Hu, X Zhou, Z Xiong, C Zhang… - Scientific Reports, 2017 - nature.com
Scar formation is an intractable medical problem that appears after skin wounds have
healed. Recent research has shown that exosomes secreted by human adipose …

[HTML][HTML] Extracellular vesicles from adipose-derived mesenchymal stem/stromal cells accelerate migration and activate AKT pathway in human keratinocytes and …

A da Fonseca Ferreira, P da Silva Cunha… - Stem Cells …, 2017 - ncbi.nlm.nih.gov
Mesenchymal stem/stromal cells (MSCs) are promising tools in cell therapy. They secrete
extracellular vesicles (EVs) that carry different classes of molecules that can promote skin …

[HTML][HTML] Adipose-derived stromal cells overexpressing vascular endothelial growth factor accelerate mouse excisional wound healing

A Nauta, C Seidel, L Deveza, D Montoro, M Grova… - Molecular Therapy, 2013 - cell.com
Angiogenesis is essential to wound repair, and vascular endothelial growth factor (VEGF) is
a potent factor to stimulate angiogenesis. Here, we examine the potential of VEGF …

[HTML][HTML] Adipose mesenchymal stem cell-derived exosomes promote wound healing through the WNT/β-catenin signaling pathway in dermal fibroblasts

C Li, Y An, Y Sun, F Yang, Q Xu, Z Wang - Stem Cell Reviews and Reports, 2022 - Springer
The differentiation, migration, and proliferation of skin fibroblasts are identified as key factors
in cutaneous wound healing. Adipose-derived mesenchymal stem cells (ADMSCs) and their …