Lipoprotein (a) in atherosclerosis: from pathophysiology to clinical relevance and treatment options

A Rehberger Likozar, M Zavrtanik… - Annals of medicine, 2020 - Taylor & Francis
Abstract Lipoprotein (a)(Lp (a)) was discovered more than 50 years ago, and a decade later,
it was recognized as a risk factor for coronary artery disease. However, it has gained …

[HTML][HTML] Lipoprotein (a) in atherosclerotic diseases: from pathophysiology to diagnosis and treatment

S Lampsas, M Xenou, E Oikonomou, P Pantelidis… - Molecules, 2023 - mdpi.com
Lipoprotein (a)(Lp (a)) is a low-density lipoprotein (LDL) cholesterol-like particle bound to
apolipoprotein (a). Increased Lp (a) levels are an independent, heritable causal risk factor …

Existing and emerging strategies to lower Lipoprotein (a)

GG Schwartz, CM Ballantyne - Atherosclerosis, 2022 - Elsevier
Abundant evidence links elevated levels of lipoprotein (a)(Lp (a)) to higher cardiovascular
risk, leaving clinicians with the challenge of what measures to take to mitigate Lp (a) …

Lipoprotein (a)-link between atherogenesis and thrombosis

D Labudovic, I Kostovska, KT Trajkovska… - Prague Medical …, 2019 - repository.ukim.mk
Lipoprotein (a)-Lp (a)-is an independent risk factor for cardiovascular disease (CVD).
Indeed, individuals with plasma concentrations of Lp (a)> 200 mg/l carry an increased risk of …

What do we know about the role of lipoprotein (a) in atherogenesis 57 years after its discovery?

B Cybulska, L Kłosiewicz-Latoszek, PE Penson… - Progress in …, 2020 - Elsevier
Elevated circulating concentrations of lipoprotein (a)[Lp (a)] is strongly associated with
increased risk of atherosclerotic cardiovascular disease (CVD) and degenerative aortic …

Lipoprotein (a): a genetic marker for cardiovascular disease and target for emerging therapies

A Cesaro, A Schiavo, E Moscarella… - Journal of …, 2021 - journals.lww.com
Abstract Lipoprotein (a)[Lp (a)] is an established cardiovascular risk factor, and growing
evidence indicates its causal association with atherosclerotic disease because of the …

Lipoprotein (a) and atherosclerotic cardiovascular disease: current understanding and future perspectives

MF Wu, KZ Xu, YG Guo, J Yu, Y Wu, LM Lin - Cardiovascular Drugs and …, 2019 - Springer
Purpose To review current knowledge of elevated lipoprotein (a)[Lp (a)] levels in relation to
atherosclerotic cardiovascular disease (ASCVD) and discuss their potential use as …

Update on lipoprotein (a) as a cardiovascular risk factor and mediator

MB Boffa, ML Koschinsky - Current atherosclerosis reports, 2013 - Springer
Recent genetic studies have put the spotlight back onto lipoprotein (a)[Lp (a)] as a causal
risk factor for coronary heart disease. However, there remain significant gaps in our …

Role of lipoprotein (a) in atherosclerotic cardiovascular disease: A review of current and emerging therapies

IS Alhomoud, A Talasaz, A Mehta… - … : The Journal of …, 2023 - Wiley Online Library
Abstract Lipoprotein (a), or Lp (a), is structurally like low‐density lipoprotein (LDL) but differs
in that it contains glycoprotein apolipoprotein (a)[apo (a)]. Due to its prothrombotic and …

Lipoprotein (a) and Cardiovascular Diseases―Revisited―

AY Jang, SH Han, IS Sohn, PC Oh, KK Koh - Circulation Journal, 2020 - jstage.jst.go.jp
Two decades ago, it was recognized that lipoprotein (a)(Lp (a)) concentrations were
elevated in patients with cardiovascular disease (CVD). However, the importance of Lp (a) …