[HTML][HTML] AZU1 (HBP/CAP37) and PRKCG (PKC-gamma) may be candidate genes affecting the severity of acute mountain sickness

Z Xu, Q Li, X Shen - BMC Medical Genomics, 2023 - Springer
Abstract Background Acute Mountain Sickness (AMS) is one of the diseases that predispose
to sudden ascent to high altitudes above 2500 m. Among the many studies on the …

A preliminary genome-wide association study of acute mountain sickness susceptibility in a group of Nepalese pilgrims ascending to 4380 m

MJ MacInnis, N Widmer, U Timulsina… - … Altitude Medicine & …, 2015 - liebertpub.com
Abstract MacInnis, Martin J., Nadia Widmer, Utsav Timulsina, Ankita Subedi, Ashmita
Siwakoti, Bidur Prasad Pandit, Michael G. Freeman, Eric A. Carter, Irina Manokhina, Ghan …

[HTML][HTML] Plasma proteomic study of acute mountain sickness susceptible and resistant individuals

H Lu, R Wang, W Li, H Xie, C Wang, Y Hao, Y Sun… - Scientific Reports, 2018 - nature.com
Although extensive studies have focused on the development of acute mountain sickness
(AMS), the exact mechanisms of AMS are still obscure. In this study, we used isobaric tags …

HSPA1A gene polymorphism rs1008438 is associated with susceptibility to acute mountain sickness in Han Chinese individuals

Z Liu, H Chen, T Xu, X Wang… - Molecular genetics & …, 2020 - Wiley Online Library
Background Acute mountain sickness (AMS) usually occurs among non‐acclimated
individuals after rapid ascending to high‐altitude environments (generally≥ 2,500 m) …

[HTML][HTML] IL-10 dysregulation in acute mountain sickness revealed by transcriptome analysis

B Liu, J Chen, L Zhang, Y Gao, J Cui, E Zhang… - Frontiers in …, 2017 - frontiersin.org
Acute mountain sickness (AMS), which may progress to life-threatening high-altitude
cerebral edema, is a major threat to millions of people who live in or travel to high altitude …

[HTML][HTML] Investigation of the gene co-expression network and hub genes associated with acute mountain sickness

Y Chang, J He, J Tang, K Chen, Z Wang, Q Xia, H Li - Hereditas, 2020 - Springer
Background Acute mountain sickness has become a heavily researched topic in recent
years. However, the genetic mechanism and effects have not been elucidated. Our goal is to …

[HTML][HTML] Potential plasma biomarkers at low altitude for prediction of acute mountain sickness

H Guo, Q Wang, T Li, J Chen, C Zhang, Y Xu… - Frontiers in …, 2023 - frontiersin.org
Background Ascending to high altitude can induce a range of physiological and molecular
alterations, rendering a proportion of lowlanders unacclimatized. The prediction of acute …

[HTML][HTML] EPAS1 and VEGFA gene variants are related to the symptoms of acute mountain sickness in Chinese Han population: a cross-sectional study

JH Zhang, Y Shen, C Liu, J Yang, YQ Yang… - Military Medical …, 2020 - Springer
Background More people ascend to high altitude (HA) for various activities, and some
individuals are susceptible to HA illness after rapidly ascending from plains. Acute mountain …

[HTML][HTML] Proteomic and clinical biomarkers for acute mountain sickness in a longitudinal cohort

J Yang, Z Jia, X Song, J Shi, X Wang, X Zhao… - Communications …, 2022 - nature.com
Ascending to high-altitude by non-high-altitude natives is a well-suited model for studying
acclimatization to extreme environments. Acute mountain sickness (AMS) is frequently …

Plasma cytokine profiling to predict susceptibility to acute mountain sickness

H Lu, R Wang, W Li, H Xie, C Wang, Y Hao… - European Cytokine …, 2016 - Springer
Extensive studies have been performed on acute mountain sickness (AMS), but biomarkers
predicting AMS are lacking. Presently, the mainstay methods to identify AMS biomarkers …