Overweight and obesity may cause several metabolic complications, including type 2
diabetes mellitus and hyperlipidemia. Despite years of progress in medicine, there are no …

Objective Celastrol, a triterpene from the root bark of the Chinese medicinal plant
Tripterygium wilfordii, has been shown to exhibit anti-oxidant, anti-inflammatory, anti-cancer …

Celastrol, a natural triterpene from the Tripterygium wilfordii has been demonstrated to
possess attributive properties to attenuate various animal models of obesity-associated …

Celastrol, a natural triterpene, has been shown to treat obesity and its related metabolic
disorders. In this study, we first assessed the relationship between the antiobesity effects of …

Celastrol is a pentacyclic triterpenoid isolated from Tripterygium wilfordii that has long been
used in traditional Chinese medicine for treating rheumatoid arthritis. Previous studies …

Celastrol is a natural pentacyclic triterpene extracted from the roots of Tripterygium wilfordi
(thunder god vine). Celastrol was reported as a powerful anti-obesity drug with leptin …

Celastrol, a plant-derived constituent of traditional Chinese medicine, has been proposed to
offer significant potential as an antiobesity drug. However, the molecular mechanism for this …

Despite all modern advances in medicine, an effective drug treatment of obesity has not
been found yet. Discovery of leptin two decades ago created hopes for treatment of obesity …

Metabolic diseases are becoming increasingly common in modern society. Therefore, it is
essential to develop effective drugs or new treatments for metabolic diseases. As an active …

Lipid metabolism disorders are pivotal in the development of various lipid-related diseases,
such as obesity, atherosclerosis, non-alcoholic fatty liver disease, type 2 diabetes, and …