Process evaluation within pragmatic randomised controlled trials: what is it, why is it done, and can we find it?—a systematic review
Background Process evaluations are increasingly conducted within pragmatic randomised
controlled trials (RCTs) of health services interventions and provide vital information to …
controlled trials (RCTs) of health services interventions and provide vital information to …
Designing process evaluations using case study to explore the context of complex interventions evaluated in trials
A Grant, C Bugge, M Wells - Trials, 2020 - Springer
Background Process evaluations are an important component of an effectiveness evaluation
as they focus on understanding the relationship between interventions and context to …
as they focus on understanding the relationship between interventions and context to …
Use of PRECIS ratings in the National Institutes of Health (NIH) health care systems research Collaboratory
KE Johnson, G Neta, LM Dember, GD Coronado… - Trials, 2016 - Springer
Abstract Background The National Institutes of Health (NIH) Health Care Systems Research
Collaboratory (NIH Collaboratory) seeks to produce generalizable knowledge about the …
Collaboratory (NIH Collaboratory) seeks to produce generalizable knowledge about the …
The ethical challenges raised in the design and conduct of pragmatic trials: an interview study with key stakeholders
Background There is a concern that the apparent effectiveness of interventions tested in
clinical trials may not be an accurate reflection of their actual effectiveness in usual practice …
clinical trials may not be an accurate reflection of their actual effectiveness in usual practice …
Readiness assessment for pragmatic trials (RAPT): a model to assess the readiness of an intervention for testing in a pragmatic trial
Background Pragmatic randomized, controlled trials (PCTs) test the effectiveness of
interventions implemented in routine clinical practice. Because PCT findings are …
interventions implemented in routine clinical practice. Because PCT findings are …
Framing the conversation: use of PRECIS-2 ratings to advance understanding of pragmatic trial design domains
PD Lipman, K Loudon, L Dluzak, R Moloney… - Trials, 2017 - Springer
Background There continues to be debate about what constitutes a pragmatic trial and how
it is distinguished from more traditional explanatory trials. The NIH Pragmatic Trials …
it is distinguished from more traditional explanatory trials. The NIH Pragmatic Trials …
Patient-reported outcomes and target effect sizes in pragmatic randomized trials in ClinicalTrials. gov: A cross-sectional analysis
Background Use of patient-reported outcomes (PROs) and patient and public engagement
are critical ingredients of pragmatic trials, which are intended to be patient centered …
are critical ingredients of pragmatic trials, which are intended to be patient centered …
Providing trial results to participants in phase III pragmatic effectiveness RCTs: a scoping review
H Bruhn, EJ Cowan, MK Campbell, L Constable… - Trials, 2021 - Springer
Background There is an ethical imperative to offer the results of trials to those who
participated. Existing research highlights that less than a third of trials do so, despite the …
participated. Existing research highlights that less than a third of trials do so, despite the …
Process Evaluation of Complex Interventions Guidance: UK Medical Research Council (MRC) Guidance
Updated MRC guidance for evaluation of complex interventions published in 2008 (Craig et
al. 2008) highlighted the value of process evaluation within trials of complex interventions in …
al. 2008) highlighted the value of process evaluation within trials of complex interventions in …
Process evaluation of complex interventions: Medical Research Council guidance
Process evaluation of complex interventions: Medical Research Council guidance Page 1
ReseaRch Methods & RepoRting 1 the bmj | BMJ 2015;350:h1258 | doi: 10.1136/bmj.h1258 …
ReseaRch Methods & RepoRting 1 the bmj | BMJ 2015;350:h1258 | doi: 10.1136/bmj.h1258 …