Carcinoembryonic antigen as a vaccine target
D Wang, S Rayani, JL Marshall - Expert review of vaccines, 2008 - Taylor & Francis
We seek to understand and harness our immune systems almost to the same degree as we
have sought the answers of the universe. It is gratifying to see that we are making progress …
have sought the answers of the universe. It is gratifying to see that we are making progress …
Efficient induction of T‐cell responses to carcinoembryonic antigen by a heterologous prime‐boost regimen using DNA and adenovirus vectors carrying a codon …
C Mennuni, F Calvaruso, A Facciabene… - … journal of cancer, 2005 - Wiley Online Library
The immunogenic properties of plasmid DNA and recombinant adenovirus (Ad) encoding
the carcinoembryonic antigen (CEA) were examined in mice by measuring both the …
the carcinoembryonic antigen (CEA) were examined in mice by measuring both the …
Induction of protective host immunity to carcinoembryonic antigen (CEA), a self-antigen in CEA transgenic mice, by immunizing with a recombinant vaccinia-CEA virus
E Kass, J Schlom, J Thompson, F Guadagni… - Cancer research, 1999 - AACR
Human carcinoembryonic antigen (CEA) is a well-characterized oncofetal glycoprotein
whose overexpression by human carcinomas has been a target for cancer immunotherapy …
whose overexpression by human carcinomas has been a target for cancer immunotherapy …
Carcinoembryonic antigen as a target to induce anti-tumor immune responses
P Sarobe, E Huarte, JJ Lasarte… - Current cancer drug …, 2004 - ingentaconnect.com
Identification of relevant targets for cancer therapy is a major goal in cancer research. In this
field, the identification of tumor antigens has opened the possibility of inducing specific anti …
field, the identification of tumor antigens has opened the possibility of inducing specific anti …
Novel mouse model for carcinoembryonic antigen-based therapy
CHF Chan, CP Stanners - Molecular therapy, 2004 - cell.com
Many novel cancer therapies, including immunotherapy and gene therapy, are specifically
targeted to tumor-associated molecules, among which carcinoembryonic antigen (CEA) …
targeted to tumor-associated molecules, among which carcinoembryonic antigen (CEA) …
Carcinoembryonic antigen as a vaccine target
J Schlom, KY Tsang, JW Hodge, JW Greiner - Cancer Immunology, 2001 - Springer
The human carcinoembryonic antigen (CEA) as a target for vaccine-mediated therapy of a
range of human cancers will be reviewed. The first section will provide an overview of the …
range of human cancers will be reviewed. The first section will provide an overview of the …
Mouse models expressing human carcinoembryonic antigen (CEA) as a transgene: evaluation of CEA-based cancer vaccines
KW Hance, HE Zeytin, JW Greiner - Mutation Research/Fundamental and …, 2005 - Elsevier
In recent years, investigators have carried out several studies designed to evaluate whether
human tumor-associated antigens might be exploited as targets for active specific …
human tumor-associated antigens might be exploited as targets for active specific …
Expression of transgenic carcinoembryonic antigen (CEA) in tumor‐prone mice: An animal model for CEA‐directed tumor immunotherapy
JA Thompson, AM Eades‐Perner… - … journal of cancer, 1997 - Wiley Online Library
Carcinoembryonic antigen (CEA) is a tumor marker for the most common forms of
adenocarcinomas. We have previously described C57BL/6 mice transgenic for the complete …
adenocarcinomas. We have previously described C57BL/6 mice transgenic for the complete …
Responses of mice immunized with a DNA vaccine encoding carcinoembryonic antigen (CEA)
S Johansson, G Engström, G Winberg, J Hinkula… - Vaccine, 2006 - Elsevier
C57BL/6 and BALB/c mice were immunized with two different plasmids (p91023B and
pKCEA66) encoding different forms of the tumor-associated antigen carcinoembryonic …
pKCEA66) encoding different forms of the tumor-associated antigen carcinoembryonic …