Expression of transgenic carcinoembryonic antigen (CEA) in tumor‐prone mice: An animal model for CEA‐directed tumor immunotherapy

JA Thompson, AM Eades‐Perner… - … journal of cancer, 1997 - Wiley Online Library
Carcinoembryonic antigen (CEA) is a tumor marker for the most common forms of
adenocarcinomas. We have previously described C57BL/6 mice transgenic for the complete …

Immunogenicity and Therapeutic Efficacy of a Dual-Component Genetic Cancer Vaccine Cotargeting Carcinoembryonic Antigen and HER2/neu in Preclinical Models

L Aurisicchio, D Peruzzi, G Koo, WZ Wei… - Human Gene …, 2014 - liebertpub.com
Several cancer vaccine efforts have been directed to simultaneously cotarget multiple tumor
antigens, with the intent to achieve broader immune responses and more effective control of …

Enhanced immune responses and anti-tumor activity by baculovirus recombinant carcinoembryonic antigen (CEA) in mice primed with the recombinant vaccinia CEA

R Bei, J Kantor, SVS Kashmiri, S Abrams… - Journal of …, 1994 - journals.lww.com
Carcinoembryonic antigen (CEA), a glycosylated protein of Mr 180, is one of the most widely
studied oncofetal antigens. A majority of gastrointestinal cancers as well as breast and non …

[HTML][HTML] Carcinoembryonic antigen

VL Kankanala, SKR Mukkamalla - 2022 - europepmc.org
Carcinoembryonic antigen (CEA) is a non-specific serum biomarker that is elevated in
various malignancies such as colorectal cancer, medullary thyroid cancer, breast cancer …

Human autoantibodies to carcinoembryonic antigen (CEA) induced by a vaccinia-CEA vaccine

RM Conry, KO Allen, S Lee, SE Moore, DR Shaw… - Clinical cancer …, 2000 - AACR
Carcinoembryonic antigen (CEA) is a well-characterized oncofetal glycoprotein whose
overexpression by human adenocarcinomas has been a target for cancer immunotherapy …

Colorectal cancer vaccines: what we know and what we don't yet know

M von Mehren - Seminars in oncology, 2005 - Elsevier
Humans have a sophisticated immune system that functions to clear invading organisms
and abnormal cells. However, cancers are able to arise despite this immune system …

Induction of mucosal and systemic immune responses against human carcinoembryonic antigen by an oral vaccine

Y Huang, R Fayad, A Smock, AM Ullrich, L Qiao - Cancer research, 2005 - AACR
Carcinoembryonic antigen (CEA) is a tumor-associated antigen targeted for the
development of colorectal tumor vaccines. In this study, we developed papillomavirus …

Carcinoembryonic antigen as a target for cancer vaccines.

JW Hodge - Cancer Immunology, Immunotherapy: CII, 1996 - europepmc.org
The vaccine approach to cancer therapy is still in the early stages. Since any immune
response has a limited capacity, immunotherapeutic manipulations to destroy tumor will …

Novel vaccines for the treatment of gastrointestinal cancers

JL Marshall - Oncology, 2005 - go.gale.com
Continuing advances in immunology and molecular biology during the past several decades
have provided optimism that immunomodulatory strategies may be clinically useful in …

[HTML][HTML] Tumor antigens and vaccines in colorectal cancer

Z Wu, M Yang, Y Cao - Medicine in Drug Discovery, 2022 - Elsevier
Colorectal cancer (CRC) is a common cancer in the world and also has a high death rate. It
is reported that vaccination is a great strategy for CRC. CRC vaccines are based on CRC …