Several different vaccine strategies have been evaluated and combined in an attempt to
amplify T-cell responses toward induction of antitumor immunity. The model tumor antigen …

The development of recombinant vaccines for specific immunotherapy of carcinoma
represents a novel approach for the treatment of breast cancer and other tumor types. This …

Just like any other effective immunization in medicine, cancer vaccines need to have
antigens with particular specificity and immunostimulatory features, the immune responses …

Individualized cancer vaccines based on patient-specific neoantigens are a groundbreaking
approach in oncology, offering a highly individualized treatment option for cancer patients …

2561 Background: CEA is expressed in> 90% of PC and may be an appropriate
immunotherapy target. CEA is poorly immunogenic due to immune tolerance; CAP1-6D, an …

Introduction: Although much progress has been made in the last decade (s) toward
development of effective cancer vaccines, there are still important obstacles to therapeutic …

Simple Summary Therapeutic cancer vaccines have failed to demonstrate clinical
improvements in phase III clinical trials over the past two decades. This has led to a rather …

Several cancer vaccination approaches have been developed and clinically validated in
recent times. The ultimate aim is to develop vaccines that can increase tumor …

With the development and regulatory approval of immune checkpoint inhibitors and adoptive
cell therapies, cancer immunotherapy has undergone a profound transformation over the …

Rapid progress in the definition of tumor antigens, and improved immunization methods,
bring effective cancer vaccines within reach. In this wide-ranging survey, leading clinicians …