The present study aimed to investigate the role and mechanism of action of ribonucleotide
reductase M2 (RRM2) in lung adenocarcinoma and its potential as a therapeutic target. Data …

Ribonucleotide reductase subunit M2 may play a role as a potential prognostic biomarker in
several cancers. In this study, we evaluated whether RRM2 gene expression is associated …

Background: Ribonucleoside-diphosphate reductase subunit M2 (RRM2) is the catalytic
subunit of ribonucleotide reductase and modulates the enzymatic activity, which is essential …

Lung cancer is a malignant tumor responsible for the highest mortality rate in humans. The
identification of novel functional genes is of great importance in the treatment of lung cancer …

The aim of this study was to examine the prognostic value of BRCA1, RRM1, and RRM2 in
patients with non-small cell lung cancer (NSCLC) who received adjuvant chemotherapy. A …

Background Non-small cell lung cancer (NSCLC) is a common and fatal cancer worldwide
with a very low 5-year overall survival rate. Ribonucleotide reductase M2 subunit (RRM2), a …

Background As one of the most common malignancy, lung adenocarcinoma (LUAD) is
characterized by low 5-year survival rate. This research aimed to investigate the effects of …

Recent research indicates that RBMS3 may act as a tumor suppressor gene (TSG) in
nasopharyngeal carcinoma (NPC) and esophageal squamous cell carcinoma (ESCC). It has …

Background Although there is evidence that ribonucleotide reductase subunit M2 (RRM2) is
associated with numerous cancers, pan-cancer analysis has seldom been conducted. This …

RNA-binding motif protein 10 (RBM10), one of the members of the RNA-binding protein
(RBP) family, has a tumor suppressor role in multiple cancers. However, the functional role …