PD-L1 is overexpressed on breast cancer stem cells through notch3/mTOR axis
FA Mansour, A Al-Mazrou, F Al-Mohanna… - …, 2020 - Taylor & Francis
The T-cell inhibitory molecule PD-L1 is expressed on a fraction of breast cancer cells. The
distribution of PD-L1 on the different subpopulations of breast cancer cells is not well …
distribution of PD-L1 on the different subpopulations of breast cancer cells is not well …
PD-L1 expression and tumor-infiltrating lymphocytes: revisiting the antitumor immune response potential in breast cancer
KA Schalper - Oncoimmunology, 2014 - Taylor & Francis
Upon analysis of 636 primary breast carcinoma patient samples, we have found that
programmed cell death ligand 1 (PD-L1) mRNA expression is associated with tumor …
programmed cell death ligand 1 (PD-L1) mRNA expression is associated with tumor …
PD‐L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation
S Almozyan, D Colak, F Mansour… - … journal of cancer, 2017 - Wiley Online Library
The expression of PD‐L1 in breast cancer is associated with estrogen receptor negativity,
chemoresistance and epithelial‐to‐mesenchymal transition (EMT), all of which are common …
chemoresistance and epithelial‐to‐mesenchymal transition (EMT), all of which are common …
[HTML][HTML] PD-L1 and intratumoral immune response in breast cancer
Purpose PD-L1 is thought to play an important role in the antitumor immune response. In this
study, we investigated the expression of PD-L1 within breast tumor subsets to better define …
study, we investigated the expression of PD-L1 within breast tumor subsets to better define …
Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival
M Sobral-Leite, K Van de Vijver, M Michaut… - …, 2018 - Taylor & Francis
To better understand the expression pattern of programmed death-ligand 1 (PD-L1)
expression in different breast cancer types, we characterized PD-L1 expression in tumor and …
expression in different breast cancer types, we characterized PD-L1 expression in tumor and …
Increased PD‐L1 expression in breast and colon cancer stem cells
Here we report the expression of programmed cell death ligand 1/2 (PD‐L1/L2) in breast
and colon cancer stem cells (CSC s). The stemness of these cells was confirmed by their …
and colon cancer stem cells (CSC s). The stemness of these cells was confirmed by their …
[HTML][HTML] PD-1 Independent Role of PD-L1 in Triple-Negative Breast Cancer Progression
D Alkaabi, K Arafat, S Sulaiman, AM Al-Azawi… - International journal of …, 2023 - mdpi.com
Triple-negative breast cancer (TNBC) is a type of breast malignancy characterized by a high
proliferative rate and metastatic potential leading to treatment failure, relapse, and poor …
proliferative rate and metastatic potential leading to treatment failure, relapse, and poor …
[HTML][HTML] Expression of PD-L1 and prognosis in breast cancer: a meta-analysis
M Zhang, H Sun, S Zhao, Y Wang, H Pu, Q Zhang - Oncotarget, 2017 - ncbi.nlm.nih.gov
The associations between programmed cell death ligand 1 (PD-L1) and the prognosis of
various cancers have always been a research topic of considerable interest. However, the …
various cancers have always been a research topic of considerable interest. However, the …
Prognostic significance of PD-L1 and PD-L2 in breast cancer
MZ Baptista, LO Sarian, SFM Derchain, GA Pinto… - Human pathology, 2016 - Elsevier
Summary PD-L1 and PD-L2 constitute an important antitumor immune response. In breast
cancer, their prognostic value is still to be defined. In this study, we investigate the …
cancer, their prognostic value is still to be defined. In this study, we investigate the …
Dual inhibition of STAT1 and STAT3 activation downregulates expression of PD-L1 in human breast cancer cells
Objectives: Breast cancer is the most commonly diagnosed cancer, and it is a leading cause
of cancer-related deaths in females worldwide. Triple-negative breast cancer (TNBC) …
of cancer-related deaths in females worldwide. Triple-negative breast cancer (TNBC) …