The influence of Glucose-dependent Insulinotropic Polypeptide (GIP) on human adipose tissue and fat metabolism: Implications for obesity, type 2 diabetes and Non …

SK Thondam, DJ Cuthbertson, JPH Wilding - Peptides, 2020 - Elsevier
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon like peptide (GLP-1) are
the two incretin hormones secreted by the enteroendocrine system in response to nutrient …

Glucose‐dependent insulinotropic polypeptide: from pathophysiology to therapeutic opportunities in obesity‐associated disorders

E Paschetta, M Hvalryg, G Musso - obesity reviews, 2011 - Wiley Online Library
Glucose‐dependent insulinotropic polypeptide (GIP) is a hormone secreted from the
intestinal K‐cells with established insulin‐releasing actions. However, the GIP receptor is …

Roles of glucose‐dependent insulinotropic polypeptide in diet‐induced obesity

Y Seino, Y Yamazaki - Journal of Diabetes Investigation, 2022 - Wiley Online Library
Glucose‐dependent insulinotropic polypeptide (GIP) and glucagon‐like peptide‐1 (GLP‐1)
are incretins that play an important role in glucose metabolism, by increasing glucose …

GIP as a therapeutic target in diabetes and obesity: insight from incretin co-agonists

JJ Holst, MM Rosenkilde - The Journal of Clinical Endocrinology …, 2020 - academic.oup.com
The 2 hormones responsible for the amplification of insulin secretion after oral as opposed
to intravenous nutrient administration are the gut peptides, glucagon-like peptide-1 (GLP-1) …

Glucose‐dependent insulinotropic polypeptide modulates adipocyte lipolysis and reesterification

L Getty‐Kaushik, DH Song, MO Boylan, BE Corkey… - …, 2006 - Wiley Online Library
Objective: Glucose‐dependent insulinotropic polypeptide (GIP) is an incretin released from
intestinal K‐cells during the postprandial period. Previous studies have suggested that GIP …

Reappraisal of GIP pharmacology for metabolic diseases

B Finan, TD Müller, C Clemmensen… - Trends in Molecular …, 2016 - cell.com
Glucagon-like peptide-1 (GLP-1) analogs are considered the best current medicines for type
2 diabetes (T2D) and obesity due to their actions in lowering blood glucose and body …

Effects on pancreatic Beta and other Islet cells of the glucose-dependent insulinotropic polypeptide

R Khan, A Tomas, GA Rutter - Peptides, 2020 - Elsevier
Glucose-dependent insulinotropic polypeptide (GIP) is a gut-derived incretin that, in
common with glucagon-like peptide-1 (GLP-1), has both insulin releasing and extra …

Glucose-dependent insulinotropic polypeptide has impaired effect on abdominal, subcutaneous adipose tissue metabolism in obese subjects

M Asmar, L Simonsen, N Arngrim, JJ Holst… - International journal of …, 2014 - nature.com
Objective: Glucose-dependent insulinotropic polypeptide (GIP) appears to have a role in
lipid metabolism. Recently, we showed that GIP in combination with hyperinsulinemia and …

GIP or not GIP? That is the question

TJ Kieffer - Trends in pharmacological sciences, 2003 - cell.com
Glucose-dependent insulinotropic polypeptide (GIP) is a gastrointestinal hormone that is
released during a meal and facilitates the disposal of both glucose and fat. Because of the i# …

GIP as a potential therapeutic agent?

JJ Meier, MA Nauck - Hormone and metabolic research, 2004 - thieme-connect.com
Glucose-dependent insulinotropic polypeptide (GIP) is released from K-cells in the gut after
meal ingestion, and acts in concert with glucagon-like peptide 1 (GLP-1) to augment glucose …