Lipoprotein (a) and inflammation-pathophysiological links and clinical implications for cardiovascular disease

S Simantiris, AS Antonopoulos, C Papastamos… - Journal of Clinical …, 2023 - Elsevier
The role of lipoprotein (a)(Lp [a]) as a significant and possibly causal cardiovascular disease
(CVD) risk factor has been well established. Many studies, mostly experimental, have …

Lipoprotein (a) and inflammation: a dangerous duet leading to endothelial loss of integrity

M Pirro, V Bianconi, F Paciullo, MR Mannarino… - Pharmacological …, 2017 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] is an enigmatic lipoprotein whose ancestral useful properties
have been gradually obscured by its adverse pro-atherogenic and pro-thrombotic effects …

Enigmatic role of lipoprotein (a) in cardiovascular disease

E Anuurad, B Enkhmaa… - Clinical and translational …, 2010 - Wiley Online Library
Abstract Lipoprotein (a),[Lp (a)] has many properties in common with low‐density
lipoprotein,(LDL) but contains a unique protein apolipoprotein (a), linked to apolipoprotein B …

[HTML][HTML] Lipoprotein (a) in atherosclerotic diseases: from pathophysiology to diagnosis and treatment

S Lampsas, M Xenou, E Oikonomou, P Pantelidis… - Molecules, 2023 - mdpi.com
Lipoprotein (a)(Lp (a)) is a low-density lipoprotein (LDL) cholesterol-like particle bound to
apolipoprotein (a). Increased Lp (a) levels are an independent, heritable causal risk factor …

[HTML][HTML] Beyond Lipoprotein (a) plasma measurements: Lipoprotein (a) and inflammation

G Reyes-Soffer, M Westerterp - Pharmacological research, 2021 - Elsevier
Genome wide association, epidemiological, and clinical studies have established high
lipoprotein (a)[Lp (a)] as a causal risk factor for atherosclerotic cardiovascular disease …

[HTML][HTML] Lipoprotein (a): an underestimated inflammatory mastermind

KE Dzobo, JM Kraaijenhof, ESG Stroes… - Atherosclerosis, 2022 - Elsevier
Abstract Lipoprotein (a)[Lp (a)] has been established as an independent and causal risk
factor for cardiovascular disease. Individuals with elevated levels of Lp (a)(> 125 nmol/L;> …

[HTML][HTML] Lipoprotein (a)—the crossroads of atherosclerosis, atherothrombosis and inflammation

S Ugovšek, M Šebeštjen - Biomolecules, 2021 - mdpi.com
Increased lipoprotein (a)(Lp (a)) levels are an independent predictor of coronary artery
disease (CAD), degenerative aortic stenosis (DAS), and heart failure independent of CAD …

[HTML][HTML] Lipoprotein (a), inflammation, and atherosclerosis

SA Di Fusco, AP Maggioni, P Scicchitano… - Journal of clinical …, 2023 - mdpi.com
Growing evidence has shown that high levels of lipoprotein (a)(Lp (a)) and chronic
inflammation may be responsible for the residual risk of cardiovascular events in patients …

Update on lipoprotein (a) as a cardiovascular risk factor and mediator

MB Boffa, ML Koschinsky - Current atherosclerosis reports, 2013 - Springer
Recent genetic studies have put the spotlight back onto lipoprotein (a)[Lp (a)] as a causal
risk factor for coronary heart disease. However, there remain significant gaps in our …

Lipoprotein (a) in atherosclerosis: from pathophysiology to clinical relevance and treatment options

A Rehberger Likozar, M Zavrtanik… - Annals of medicine, 2020 - Taylor & Francis
Abstract Lipoprotein (a)(Lp (a)) was discovered more than 50 years ago, and a decade later,
it was recognized as a risk factor for coronary artery disease. However, it has gained …