Application of electrospun materials in gene delivery

GSNK Rao, M Kurakula… - Electrospun Materials and …, 2020 - Wiley Online Library
Gene therapy has emerged as a promising strategy for treatment of many acquired or
inherited diseases providing ample benefits over conventional therapies. Even the cost …

Electrospun nanofibrous scaffolds for biomedical applications

JB Chiu, YK Luu, D Fang, BS Hsiao… - Journal of …, 2005 - ingentaconnect.com
Within the last few years there has been an explosive growth in published reports on the use
of electrospinning as a method of generating scaffolds intended for biomedical applications …

Electrospun nanofibers for drug delivery in regenerative medicine

S Nagarajan, M Bechelany, NS Kalkura, P Miele… - Applications of targeted …, 2019 - Elsevier
Inherent physical properties such as high surface area and extracellular matrix mimicking
structure of electrospun fibers are advantageous for loading the drug/biomolecule. Also …

Electrospun nanofiber scaffolds: Technology and applications

PP Mehta, VS Pawar - Applications of nanocomposite materials in drug …, 2018 - Elsevier
Presently, the field of nanotechnology is growing rapidly and playing a valuable role in
advancing the knowledge of material science to boost health benefits. The impact of …

Electrospun drug-loaded and gene-loaded nanofibres: the holy grail of glioblastoma therapy?

L Louis, BS Chee, M McAfee, M Nugent - Pharmaceutics, 2023 - mdpi.com
To date, GBM remains highly resistant to therapies that have shown promising effects in
other cancers. Therefore, the goal is to take down the shield that these tumours are using to …

Synthetic-based blended electrospun scaffolds in tissue engineering applications

Z Mohammadalizadeh, E Bahremandi-Toloue… - Journal of Materials …, 2022 - Springer
Electrospinning, as one of the most common methodologies in nanofibers production,
involves applying high voltages to a polymeric solution that is entrapped in a syringe to …

The significance of electrospinning as a method to create fibrous scaffolds for biomedical engineering and drug delivery applications

A Repanas, S Andriopoulou, B Glasmacher - Journal of Drug Delivery …, 2016 - Elsevier
The unique properties of fibers have received great attention from the scientific community
as suitable candidates for biomedical engineering and drug delivery applications. Their …

Electrospun-fibrous-architecture-mediated non-viral gene therapy drug delivery in regenerative medicine

E Cojocaru, J Ghitman, R Stan - Polymers, 2022 - mdpi.com
Gene-based therapy represents the latest advancement in medical biotechnology. The
principle behind this innovative approach is to introduce genetic material into specific cells …

Electrospun nanofibrous scaffolds-current status and prospects in drug delivery

M Prabaharan, R Jayakumar, SV Nair - Biomedical applications of …, 2012 - Springer
Controlled delivery systems are used to improve therapeutic efficacy and safety of drugs by
delivering them over a period of treatment to the site of action at a rate dictated by the need …

Conventional electrospinning vs. emulsion electrospinning: a comparative study on the development of nanofibrous drug/biomolecule delivery vehicles

C Wang, SN Tong, YH Tse, M Wang - Advanced Materials …, 2012 - Trans Tech Publ
Over the past decade, intensive research has been conducted on electrospinning of fibrous
tissue engineering scaffolds and their applications in body tissue regeneration. For …