How I investigate acute myeloid leukemia

D Narayanan, OK Weinberg - International journal of laboratory …, 2020 - Wiley Online Library
Acute myeloid leukemia (AML) is a neoplasm of immature myeloid cells and is associated
with a wide variety of clinical presentations, morphological features, immunophenotypes …

[HTML][HTML] Acute myeloid leukemia—genetic alterations and their clinical prognosis

FA Lagunas-Rangel, V Chávez-Valencia… - … journal of hematology …, 2017 - ncbi.nlm.nih.gov
Acute myeloid leukemia (AML) is a group of hematological diseases, phenotypic and
genetically heterogeneous, characterized by abnormal accumulation of blast cells in the …

[HTML][HTML] Molecular characterization of acute myeloid leukemia

K Döhner, H Döhner - Haematologica, 2008 - haematologica.org
Acute myeloid leukemia (AML) is a genetically heterogeneous clonal disorder characterized
by the accumulation of acquired somatic genetic alterations in hematopoietic progenitor …

Acute myeloid leukaemia

A Khwaja, M Bjorkholm, RE Gale, RL Levine… - Nature reviews Disease …, 2016 - nature.com
Acute myeloid leukaemia (AML) is a disorder characterized by a clonal proliferation derived
from primitive haematopoietic stem cells or progenitor cells. Abnormal differentiation of …

Childhood acute myeloid leukaemia

JE Rubnitz, H Inaba - British journal of haematology, 2012 - Wiley Online Library
Although acute myeloid leukaemia (AML) has long been recognized for its morphological
and cytogenetic heterogeneity, recent high‐resolution genomic profiling has demonstrated a …

Acute myeloid leukemia

A Heerema-McKenney, DA Arber - Hematology/oncology clinics of North …, 2009 - Elsevier
The evolution of acute myeloid leukemia (AML) classification reflects greater understanding
of the AML pathogenesis. The 2008 World Health Organization classification incorporated …

Advances in understanding the biology and genetics of acute myelocytic leukemia

SB McKenzie - American Society for Clinical Laboratory Science, 2005 - clsjournal.ascls.org
Acute myelocytic leukemia (AML) is a malignant neoplasm of hematopoietic cells
characterized by an abnormal proliferation of myeloid precursor cells, decreased rate of self …

The International Consensus Classification of acute myeloid leukemia

OK Weinberg, A Porwit, A Orazi, RP Hasserjian… - Virchows Archiv, 2023 - Springer
Acute myeloid leukemias (AMLs) are overlapping hematological neoplasms associated with
rapid onset, progressive, and frequently chemo-resistant disease. At diagnosis, classification …

Mutations in AML: prognostic and therapeutic implications

CD DiNardo, JE Cortes - Hematology 2014, the American …, 2016 - ashpublications.org
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized
by the proliferation and aberrant differentiation of immature clonal myeloid cells. The …

[HTML][HTML] Cytogenetics of pediatric acute myeloid leukemia: a review of the current knowledge

J Quessada, W Cuccuini, P Saultier, M Loosveld… - Genes, 2021 - mdpi.com
Pediatric acute myeloid leukemia is a rare and heterogeneous disease in relation to
morphology, immunophenotyping, germline and somatic cytogenetic and genetic …