Multiple sclerosis–a response-to-damage model
BA't Hart, RQ Hintzen, JD Laman - Trends in molecular medicine, 2009 - cell.com
According to a widely supported but unproven concept, the autoimmune mechanisms that
drive neuroinflammation in multiple sclerosis (MS) are triggered by virus infection. However …
drive neuroinflammation in multiple sclerosis (MS) are triggered by virus infection. However …
[PDF][PDF] Viruses and neuroinflammation in multiple sclerosis
R Mechelli, C Romano, R Reniè, G Manfrè… - Neuroimmunology and …, 2021 - academia.edu
In multiple sclerosis (MS), a relationship with viral infection has long been recognized,
starting from clinical evidence of an association between infectious events and disease …
starting from clinical evidence of an association between infectious events and disease …
The enigmatic role of viruses in multiple sclerosis: molecular mimicry or disturbed immune surveillance?
Multiple sclerosis (MS) is a T cell driven autoimmune disease of the central nervous system
(CNS). Despite its association with Epstein-Barr Virus (EBV), how viral infections promote …
(CNS). Despite its association with Epstein-Barr Virus (EBV), how viral infections promote …
A complex role of herpes viruses in the disease process of multiple sclerosis
SC Wuest, I Mexhitaj, NR Chai, E Romm, J Scheffel… - PLoS …, 2014 - journals.plos.org
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system
(CNS). Neither the antigenic target (s) nor the cell population (s) responsible for CNS tissue …
(CNS). Neither the antigenic target (s) nor the cell population (s) responsible for CNS tissue …
[HTML][HTML] Viral triggers of multiple sclerosis
K Kakalacheva, C Münz, JD Lünemann - Biochimica et Biophysica Acta …, 2011 - Elsevier
Genetic and environmental factors jointly determine the susceptibility to develop Multiple
Sclerosis (MS). Collaborative efforts during the past years achieved substantial progress in …
Sclerosis (MS). Collaborative efforts during the past years achieved substantial progress in …
[HTML][HTML] Mimicking the brain: Epstein-Barr virus and foreign agents as drivers of neuroimmune attack in multiple sclerosis
OG Thomas, T Olsson - Frontiers in Immunology, 2023 - frontiersin.org
T cells have an essential role in adaptive immunity against pathogens and cancer, but
failure of thymic tolerance mechanisms can instead lead to escape of T cells with the ability …
failure of thymic tolerance mechanisms can instead lead to escape of T cells with the ability …
Gene–environment interactions in multiple sclerosis: innate and adaptive immune responses to human endogenous retrovirus and herpesvirus antigens and the lectin …
Aspects of gene-environment interactions in multiple sclerosis (MS) were analysed in serum
samples from 46 MS families (25 sporadic MS cases and 42 familial MS cases): antibodies …
samples from 46 MS families (25 sporadic MS cases and 42 familial MS cases): antibodies …
Asymptomatic herpes simplex virus type 1 infection causes an earlier onset and more severe experimental autoimmune encephalomyelitis
LF Duarte, MJ Altamirano-Lagos… - Frontiers in …, 2021 - frontiersin.org
Multiple sclerosis (MS) is an increasingly prevalent progressive autoimmune and debilitating
chronic disease that involves the detrimental recognition of central nervous system (CNS) …
chronic disease that involves the detrimental recognition of central nervous system (CNS) …
Herpesviruses and the hidden links to Multiple Sclerosis neuropathology
Abstract Herpesviruses like Epstein-Barr virus, human herpesvirus (HHV)-6, HHV-1, VZV,
and human endogenous retroviruses, have an age-old clinical association with multiple …
and human endogenous retroviruses, have an age-old clinical association with multiple …
Viral infections and multiple sclerosis
D Donati - Drug Discovery Today: Disease Models, 2020 - Elsevier
The etiology and pathogenesis of MS is likely to involve multiple factors interacting with each
other, and the role of infectious and viral agents is still under debate, however a consistent …
other, and the role of infectious and viral agents is still under debate, however a consistent …