Intracerebral infection of susceptible strains of mice, eg SJL/J, with Theiler's murine
encephalomyelitis virus (TMEV) leads to a persistent CNS infection accompanied by …

Multiple Sclerosis (MS) is an enigmatic immune mediated disease of the central nervous
system that affects about 350,000 individuals in the US, and many more around the world …

Multiple sclerosis (MS) is an inflammatory, demyelinating, and neurodegenerative disease
of the central nervous system of uncertain etiology. There is consensus that a dysregulated …

Multiple exogenous signals received from cell surface molecules or cytokines play a
significant role in altering the host immune response. In chronic autoimmune‐mediated …

Pathogenesis of autoimmune-mediated inflammatory CNS disease. to why epitope
spreading does not occur in other forms of CNS inflammation such as stroke, where there is …

Multiple sclerosis (MS), and its animal model experimental autoimmune encephalomyelitis,
are neuroinflammatory diseases driven by autoreactive pathogenic TH cells that elicit …

The complex interactions between multiple viral infections, either within the central nervous
system or in the periphery, and the host immune response to viral infection may be such that …

Abstract “Multiple sclerosis is an autoimmune disease,” is heard so often that it is widely
accepted as fact by the current generation of students and physicians. Yet, although it is …

Substantial evidence supports autoimmune activity as the etiologic mechanism underlying
multiple sclerosis (MS). Both the innate and the adaptive arms of the immune system are …

Multiple sclerosis is the most common debilitating neurological disease in people under the
age of forty in the developed world. Many publications cover medical and clinical …