Background Monocytes/macrophages play critical roles in inflammation and cardiac
remodeling following myocardial infarction (MI). The cholinergic anti-inflammatory pathway …

Stimulation of the alpha 7 nicotinic acetylcholine receptor (α7nAChR) has shown beneficial
effects in several acute inflammatory disease models. This study aims to examine whether …

Alpha7 nicotinic acetylcholine receptor (α7nAChR) has been previously reported to play an
alleviative role in myocardial infarction (MI). In this study, we investigated its specific …

Our previous studies have reported that agonist of α7 nicotinic acetylcholine receptors
prevented electrophysiological dysfunction of rats with ischaemic cardiomyopathy (ICM) by …

Background Activation of the cholinergic anti-inflammatory pathway, which relies on the
α7nAchR (alpha 7 nicotinic acetylcholine receptor), has been shown to decrease …

The cholinergic anti‑inflammatory pathway is considered an attractive approach for the
alleviation of inflammatory diseases. Sepsis is characterized by systemic inflammation and …

Background and aims Alpha 7 nicotinic acetylcholine receptor (α7nAChR) stimulation can
regulate acute inflammation, and lack of α7nAChR accelerates atherosclerosis in mice. In …

Activation of the cholinergic anti-inflammatory pathway (CAP) via vagus nerve stimulation
has been shown to improve acute kidney injury in rodent models. While alpha 7 nicotinic …

Objective Smoking and high-sensitivity C-reactive protein (hs-CRP) are risk factors for
coronary artery spasm (CAS), which is characterized by the increased interleukin-6 (IL-6) …

The inflammatory response plays a major role in ischemia–reperfusion injury (IRI).
Considering that cholinergic stimulation can inhibit inflammatory response through the …