Oxidative modification of low-density lipoprotein (LDL) is one of the earliest events in
atherosclerosis. Oxidized LDL (oxLDL) represents a variety of modification of both lipid and …

Peroxidation of membranes and lipoproteins converts “inert” phospholipids into a plethora of
oxidatively modified phospholipids (oxPL) that can act as signaling molecules. In this review …

Oxidative modification of LDL is known to elicit an array of pro-atherogenic responses, but it
is generally underappreciated that oxidized LDL (OxLDL) exists in multiple forms …

Oxidized phospholipids (OxPLs) are known to induce in cultured cells multiple biological
effects that are potentially relevant to pathology. However, until recently it was not clear if …

Oxidation of low density lipoprotein (LDL) phospholipids containing arachidonic acid at the
sn-2 position occurs when a critical concentration of “seeding molecules” derived from the …

Atherosclerosis (AT) is a metabolic, systemic inflammatory/immune disease characterized by
lipoproteins metabolism alteration that leads to immune/inflammatory system activation with …

Oxidative modification of low density lipoprotein (LDL) is thought to play a major role in
atherogenesis (1, 2, 3). While unoxidized (native) LDL plays a physiologic role inlipid …

Oxidation of lipoproteins, and in particular low density lipoprotein (LDL), has been
implicated as a major factor in the initiation and progression of atherosclerosis^^^ Over the …

Significance: Atherosclerotic cardiovascular diseases (ACVDs) continue to be a primary
cause of mortality worldwide in adults aged 35–70 years, occurring more often in countries …

Oxidation of LDL is considered a marker of inflammation. Indeed, numerous studies have
documented that oxidized lipids as well as products derived from their decomposition have …