Hnrnpab regulates neural cell motility through transcription of Eps8

AA Lampasona, K Czaplinski - Rna, 2019 - rnajournal.cshlp.org
Cell migration requires a complicated network of structural and regulatory proteins. Changes
in cellular motility can impact migration as a result of cell-type or developmental stage …

hnRNP A1B, a Splice Variant of HNRNPA1, Is Spatially and Temporally Regulated

M Gagné, JE Deshaies, H Sidibé, Y Benchaar… - Frontiers in …, 2021 - frontiersin.org
RNA binding proteins (RBPs) play a key role in cellular growth, homoeostasis and survival
and are tightly regulated. A deep understanding of their spatiotemporal regulation is needed …

[HTML][HTML] RNA binding protein Rbms1 enables neuronal differentiation and radial migration during neocortical development by binding and stabilizing the RNA …

K Habib, K Bishayee, J Kang, A Sadra, SO Huh - Molecules and cells, 2022 - Elsevier
Various RNA-binding proteins (RBPs) are key components in RNA metabolism and
contribute to several neurodevelopmental disorders. To date, only a few of such RBPs have …

Differential subcellular distributions and trafficking functions of hnRNP A2/B1 spliceoforms

SP Han, LR Friend, JH Carson, G Korza, E Barbarese… - Traffic, 2010 - Wiley Online Library
Trafficking of mRNA molecules from the nucleus to distal processes in neural cells is
mediated by heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 trans‐acting factors …

[HTML][HTML] Sorting mRNA molecules for cytoplasmic transport and localization

N Neriec, P Percipalle - Frontiers in Genetics, 2018 - frontiersin.org
In eukaryotic cells, gene expression is highly regulated at many layers. Nascent RNA
molecules are assembled into ribonucleoprotein complexes that are then released into the …

LncRNA Pnky Positively Regulates Neural Stem Cell Migration by Modulating mRNA Splicing and Export of Target Genes

J Du, Y Li, Y Su, W Zhi, J Zhang, C Zhang… - Cellular and Molecular …, 2023 - Springer
Directed migration of neural stem cells (NSCs) is critical for embryonic neurogenesis and the
healing of neurological injuries. The long noncoding RNA (lncRNA) Pnky has been reported …

Hnrpab regulates neural development and neuron cell survival after glutamate stimulation

JR Sinnamon, CB Waddell, S Nik, EI Chen… - Rna, 2012 - rnajournal.cshlp.org
The molecular mechanisms that govern the timing and fate of neural stem-cell differentiation
toward the distinct neural lineages of the nervous system are not well defined. The …

Cytosolic Ptbp2 modulates axon growth in motoneurons through axonal localization and translation of Hnrnpr

S Salehi, A Zare, G Prezza, J Bader… - Nature …, 2023 - nature.com
The neuronal RNA-binding protein Ptbp2 regulates neuronal differentiation by modulating
alternative splicing programs in the nucleus. Such programs contribute to axonogenesis by …

The Zinc Finger Transcription Factor RP58 Negatively Regulates Rnd2 for the Control of Neuronal Migration During Cerebral Cortical Development

JIT Heng, Z Qu, C Ohtaka-Maruyama, H Okado… - Cerebral …, 2015 - academic.oup.com
The zinc finger transcription factor RP58 (also known as ZNF238) regulates neurogenesis of
the mouse neocortex and cerebellum (Okado et al. 2009; Xiang et al. 2011; Baubet et al …

Rules of engagement promote polarity in RNA trafficking

JH Carson, N Blondin, G Korza - BMC neuroscience, 2006 - Springer
Many cell biological pathways exhibit overall polarity (net movement of molecules in one
direction) even though individual molecular interactions in the pathway are freely reversible …