mRNA translation in axons eNAbles neurons to introduce new proteins at sites distant from
their cell body. mRNA-protein interactions drive this post-transcriptioNAl regulation, yet …

During embryonic development post‐mitotic neurons of the precerebellar neuroepithelium,
migrate from the rhombic lip to the ventral part of the neural tube to form the precerebellar …

Disturbed RNA processing and subcellular transport contribute to the pathomechanisms of
motoneuron diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy …

Upon nuclear export, RNP particles are either localized to polysomes or further assembled
into larger RNA granules which are transported to the cellular periphery for localized …

Neurogenesis is initiated by basic helix-loop-helix proneural proteins. Here, we show that
Actin-related protein 6 (Arp6), a core component of the H2A. Z exchange complex SWR1 …

RNA molecules are localized to specific subcellular regions through interactions between
RNA regulatory elements and RNA binding proteins (RBPs). Generally, our knowledge of …

Aebp2 is a potential targeting protein for the mammalian Polycomb Repression Complex 2
(PRC2). We generated a mutant mouse line disrupting the transcription of Aebp2 to …

Nesprins are a multi-isomeric family of spectrin-repeat (SR) proteins, predominantly known
as nuclear envelope scaffolds. However, isoforms that function beyond the nuclear envelope …

Highlights•RNA localization is highly conserved throughout evolution.•mRNPs regulate
every step of the journey from birth to death.•mRNPs movement is a combination of diffusion …

Evidence indicates that dysfunctional heterogeneous ribonucleoprotein A1 (hnRNPA1; A1)
contributes to the pathogenesis of neurodegeneration in multiple sclerosis. Understanding …