BACKGROUND: Cardiac surgery induces the release of inflammatory mediators that can
prolong cardiac dysfunction after operative intervention. Interleukin-10 (IL-10), a potent …

Myocardial ischemia-reperfusion (I/R) is a well-known stimulus for acute inflammatory
responses that promote cell death and impair pump function. Interleukin-10 (IL-10) is an …

Background—The anti-inflammatory cytokine interleukin-10 (IL-10) has been detected in the
plasma of patients with myocardial ischemia/reperfusion. The aim of our study was to …

Abstract Objective: Interleukin-10 (IL-10) exerts potent anti-inflammatory actions and
modulates matrix metalloproteinase expression. We hypothesized that endogenous IL-10 …

Background Previously, we have demonstrated the cardioprotective effect of interleukin (IL)-
11 in animal models of acute coronary syndrome. In this study, we sought to evaluate its …

Reperfusion of the ischemic myocardium is associated with a dramatic inflammatory
response leading to TNF-α release, IL-6 induction, and subsequent neutrophil-mediated …

Activation of cardiac STAT3 by IL-6 cytokine family contributes to cardioprotection.
Previously, we demonstrated that IL-11, an IL-6 cytokine family, has the therapeutic potential …

BACKGROUND Interleukin (IL)‐22, a member of the IL‐10 cytokine family, is the only known
cytokine that is secreted by immune cells but does not target immune cells; it mainly targets …

We have interestingly read an experimental study reported by Barry and colleagues
concerning “Enhanced IL-17 signaling following myocardial ischemia/reperfusion injury”[1] …

Interleukin-6 (IL-6) can cause pro-and anti-inflammatory effects via different signaling
pathways. This prospective study investigated the perioperative kinetics of IL-6, soluble IL-6 …