Establishment and assessment of pancreas preservation using oxygenated hypothermic machine perfusion
G Hakim - 2022 - ora.ox.ac.uk
Background: Pancreatic transplantation is the treatment of choice for a selected group of
patients with the most severe complications of diabetes. The two main causes of early failure …
patients with the most severe complications of diabetes. The two main causes of early failure …
[PDF][PDF] Prototype development of a system for hypothermic oxygenated perfusion of the pancreas
M Leemkuil, C Krikke, RA Pol - Strategies to improve outcome after …, 2022 - research.rug.nl
Worldwide about 422 million patients suffer from diabetes mellitus, of which 10% are
diagnosed with type 1 diabetes mellitus (T1DM), a prevalence that has doubled in the past …
diagnosed with type 1 diabetes mellitus (T1DM), a prevalence that has doubled in the past …
Ischemia-reperfusion injuries assessment during pancreas preservation
Maintaining organ viability between donation and transplantation is of critical importance for
optimal graft function and survival. To date in pancreas transplantation, static cold storage …
optimal graft function and survival. To date in pancreas transplantation, static cold storage …
Hypothermic oxygenated machine perfusion of the human donor pancreas
M Leemkuil, G Lier, MA Engelse, RJ Ploeg… - Transplantation …, 2018 - journals.lww.com
Background Transplantation of beta cells by pancreas or islet transplantation is the
treatment of choice for a selected group of patients suffering from type 1 diabetes mellitus …
treatment of choice for a selected group of patients suffering from type 1 diabetes mellitus …
Machine Perfusion of the Pancreas: What Can We Learn from five Decades of Experimental Studies?
F Staderini, M Dimitri, N Navari, A Corvi… - JOURNAL OF …, 2023 - flore.unifi.it
Background: Pancreas transplantation is currently the best option for patients with severe
complications of diabetes. This organ is however particularly vulnerable to Ischemia …
complications of diabetes. This organ is however particularly vulnerable to Ischemia …
Development of ex situ normothermic reperfusion as an innovative method to assess pancreases after preservation
AE Ogbemudia, G Hakim, F Dengu… - Transplant …, 2021 - Wiley Online Library
Static cold storage (SCS) is the standard method for pancreas preservation prior to
transplantation; however, it does not permit organ assessment. Normothermic reperfusion …
transplantation; however, it does not permit organ assessment. Normothermic reperfusion …
Machine perfusion and the pancreas: will it increase the donor pool?
K Hamaoui, V Papalois - Current Diabetes Reports, 2019 - Springer
Abstract Purpose of Review Pancreas transplantation enables complete patient
independence from exogenous insulin administration and increases both patient survival …
independence from exogenous insulin administration and increases both patient survival …
338.2: Oxygenated hypothermic machine perfusion of the pancreas; a porcine circulatory death model to compare a 'continuous' and an 'end-ischaemic'approach
MA Elzawahry, J Fallon, S Nawaz, B Hastoy… - …, 2023 - journals.lww.com
Methods: Porcine pancreases were retrieved from the abattoir after exsanguination.
Pancreases were flushed with UW cold storage solution and prepared surgically, then either …
Pancreases were flushed with UW cold storage solution and prepared surgically, then either …
234.11: Impact of Hypothermic Oxygenated PErfusion (HOPE) During Hypothermic Preservation and Normothermic Reperfusion in a Preclinical Porcine Model of …
B Mesnard, T Prudhomme, E Ogbemudia… - …, 2022 - journals.lww.com
Purpose: The proportion of pancreatic transplants from standard criteria donors (SCD) is
decreasing with a parallel increase in the number of extended criteria donors (ECD) and of …
decreasing with a parallel increase in the number of extended criteria donors (ECD) and of …
Development of ex vivo normothermic perfusion as an innovative method to assess pancreases after preservation
A Ogbemudia - Journal of the Nuffield Department of Surgical …, 2022 - journal.nds.ox.ac.uk
Objective Static cold storage (SCS) is the standard method for pancreas preservation but
does not facilitate objective organ assessment prior to transplantation. Normothermic …
does not facilitate objective organ assessment prior to transplantation. Normothermic …