Current state of hypothermic machine perfusion preservation of organs: The clinical perspective

MJ Taylor, SC Baicu - Cryobiology, 2010 - Elsevier
This review focuses on the application of hypothermic perfusion technology as a topic of
current interest with the potential to have a salutary impact on the mounting clinical …

PANCREAS EX-SITU PRESERVATION AND EVALUATION. DEVELOPMENT OF A NORMOTHERMIC MACHINE PERFUSION SYSTEM

B Mesnard, D Kervella, T Prudhomme… - European Journal …, 2023 - eujtransplantation.com
Simultaneous kidney-pancreas transplantation remains the gold standard treatment for
patients with type I diabetes and end-stage renal disease. The evolution of donor …

Normothermic ex vivo pancreas perfusion for the preservation of pancreas allografts before transplantation

C Parmentier, S Ray, L Mazilescu, M Kawamura… - JoVE (Journal of …, 2022 - jove.com
Pancreas transplantation (PTx) is a curative treatment for people who live with the burden of
a diagnosis of diabetes mellitus (DM). However, due to organ shortages and increasing …

Improved kidney graft function after preservation using a novel hypothermic machine perfusion device

MHJ Maathuis, S Manekeller, A van der Plaats… - Annals of …, 2007 - journals.lww.com
Objective: To study graft function and ischemia/reperfusion injury of porcine kidneys after
preservation with the new Groningen Machine Perfusion (GMP) system versus static cold …

[HTML][HTML] Development of Ex Situ Normothermic Reperfusion as an Innovative Method to Assess Pancreases After Preservation

A Panisello-Roselló, E Folch-Puy… - Transplant …, 2022 - frontierspartnerships.org
pancreases by normothermic reperfusion (NR), the authors suggested that HMPO2 may be
better than SCS; they a further compared two different HMPO2 perfusates: Belzer-MPS and …

[HTML][HTML] Use of ex vivo normothermic perfusion for quality assessment of discarded human donor pancreases

AD Barlow, MO Hamed, DH Mallon, RJ Brais… - American Journal of …, 2015 - Elsevier
A significant number of pancreases procured for transplantation are deemed unsuitable due
to concerns about graft quality and the associated risk of complications. However, this …

Hypothermic perfusion preservation of pancreas for islet grafts: validation using a split lobe porcine model

BP Weegman, MJ Taylor, SC Baicu, WE Scott… - 2011 - journals.sagepub.com
The demand for high-quality islets for transplantation in type I diabetics will increase as the
current clinical trials transition into standard of care. The mode of preservation of donor …

[HTML][HTML] Normothermic Ex Vivo Machine Perfusion of Discarded Human Pancreas Allografts: A Feasibility Study

C Parmentier, S Ray, LI Mazilescu… - Transplant …, 2023 - frontierspartnerships.org
Pancreas transplantation is the only curative treatment for patients with complicated
diabetes, and organ shortage is a common and increasing problem. Strategies to expand …

[HTML][HTML] Reanimating Pancreatic Grafts Subjected to Prolonged Cold Ischemic Injury Using Normothermic Ex Vivo Perfusion

S Ray, C Parmentier, M Kawamura… - Transplantation …, 2024 - journals.lww.com
Background. Pancreas transplant volumes are limited because of poor utilization of
“extended criteria grafts.” Prolonged cold ischemia is a risk factor associated with poor …

Whole pancreas transplantation: Advantages and disadvantages, and an overview of new technologies in organ resuscitation

H Pleass - Pancreas and Beta Cell Replacement, 2022 - Elsevier
This chapter concentrates on the advantages and disadvantages of solid organ pancreas
transplantation. It covers the impact of successful pancreas graft function on diabetic …