The skin is the outermost protective organ susceptible to damage by external injury and
retains undesired scars after wound healing, which often diminishes the quality of life and …

Epidermal tissue repair represents a complex series of temporal and dynamic events
resulting in wound closure. Matricellular proteins, not normally expressed in quiescent adult …

Extracellular matrix (ECM) is not only involved in the maintenance of normal physiological
tissue but also in interactions with other ECM components, tissue remodeling, and …

Objective To probe into the role of periostin in the formation of scars and investigate its
reaction to hydrocortisone. Methods Primary fibroblasts were cultured in vitro, then RT-PCR …

Differentiation of fibroblasts to myofibroblasts and collagen fibrillogenesis are two processes
essential for normal cutaneous development and repair, but their misregulation also …

Background Periostin is a secreted 90 kDa matricellular protein, which is predominantly
expressed in collagen-rich tissues. Collagen is the most abundant protein in mammals and …

Periostin is a matricellular protein involved in development, maintenance, and regulation of
tissues and organs via by binding to cell surface integrin receptors. Pathologically, periostin …

Skin is a large organ that is susceptible to damage by external forces, chronic inflammation,
and autoimmune reactions. In general, tissue damage causes alterations in both the …

Objective To probe into periostin's role in the pathological mechanism of hyperplasic scars,
by examining the expression of periostin in hyperplasic scar tissues. To investigate the …

Although many studies have described the role of periostin in various diseases, the function
of the periostin protein structures derived from alternative splicing and proteinase cleavage …