Many cytokines are currently under investigation as potential target to improve cardiac
function and outcome in the setting of acute myocardial infarction (MI) or chronic heart failure …

BACKGROUND: Myocardial dysfunction has been associated with inflammation and
cytokine modulation. OBJECTIVES: The study objective was to understand the role of …

Heart failure exhibits remarkable pathophysiologic heterogeneity. A large body of evidence
suggests that regardless of the underlying etiology, heart failure is associated with induction …

Abstract Interleukin-1 (IL-1) is the prototypical pro-inflammatory cytokine that occupies an
apical place in the inflammatory cascade and also modulates cardiac function, functioning …

Rheumatoid arthritis (RA) is among the most common rheumatologic diseases, affecting
approximately 1% of the population, with millions of affected subjects worldwide [1]. In such …

Accumulating evidence indicates that inflammatory mediators are important in the
pathogenesis of chronic heart failure (CHF), contributing to cardiac remodeling and …

Proinflammatory cytokines affect nearly all tissues and organ systems, and the vasculature is
no exception. Although a considerable amount of research has focused on the role of the …

Background Atherosclerosis is a chronic inflammatory disease of the artery wall. Regulatory
T cells (Tregs) limit inflammation and promote tissue healing. Low doses of interleukin (IL)-2 …

Evidence from both experimental and clinical trials indicates that inflammatory mediators are
important in the pathogenesis of chronic heart failure (HF), contributing to cardiac …

Inflammatory cytokines may negatively influence contractility and contribute to the
remodelling process in the failing myocardium. Traditional cardiovascular drugs appear to …